|Targets||Angiotensin-converting Enzyme (ACE)|
|Description||Enalapril is an angiotensin converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies. Its IC50 values range from 2 to 800 nM. lt belongs to a class of medications called angiotensin converting enzyme inhibitors. pressure. lt decreases levels of angiotensin II leading to less vasoconstriction and decreased blood pressure by inhibiting ACE. lt has been shown to lower the death rate in systolic heart failure. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.|
|Appearance||White needle like crystal or crystalline powder|
|Synonyms||(S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-l-alanyl)-l-proline;1-(N-((S)-1-carboxy-3-phenylpropyl)-l-alanyl)-l-proline 1'-ethyl ester;Renitec;Vasotec;L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, (S)-;Enalaprilum;Enalaprila;(S)-1-((S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)aMino)propanoyl)pyrrolidine-2-carboxylic acid|
|Solubility||DMSO 99 mg/mL; Water <1 mg/Ml|
|Application||Enalapril is used in the treatment of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies. lt decreases levels of angiotensin II leading to less vasoconstriction and decreased blood pressure by inhibiting ACE. lt lowers the death rate in systolic heart failure.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Quantity||Grams to Kilograms|
|Boiling Point||582.4±50.0 °C | Condition: Press: 760 Torr|
|Melting Point||143-144 °C|
|Density||1.204±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
|Current Developer||Original research factory is Valeant. It has been approved the listing.|
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