EN460 - CAS 496807-64-8
Catalog number:
496807-64-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H12ClF3N2O4
Molecular Weight:
460.79
COA:
Inquire
Targets:
Others
Description:
EN460 is a small molecule inhibitor by EN460 binding to ERO1α to promote the loss of flavin adenine dinucleotide (FAD) from the holoenzyme(IC50=1.9 uM) .
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Purity:
≥98%
Appearance:
Solid powder
Synonyms:
2-chloro-5-[5-oxo-4-[(5-phenyl-2-furyl)methylene]-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
ERO1 Inhibitor II
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
RSLFQCNAOMQAIH-WJDWOHSUSA-N
InChI:
1S/C22H12ClF3N2O4/c23-17-8-6-13(10-15(17)21(30)31)28-20(29)16(19(27-28)22(24,25)26)11-14-7-9-18(32-14)12-4-2-1-3-5-12/h1-11H,(H,30,31)/b16-11-
Canonical SMILES:
c1ccc(cc1)c2ccc(o2)/C=C\3/C(=NN(C3=O)c4ccc(c(c4)C(=O)O)Cl)C(F)(F)F
Current Developer:
Endo Pharmaceuticals
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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