EML-425 - CAS 1675821-32-5
Catalog number: 1675821-32-5
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H24N2O4
Molecular Weight:
440.49
COA:
Inquire
Targets:
Others
Description:
EML-425, a diazinane derivative, has been found to be a CBP/p300 inhibitor that could probably be significant in studies of human leukemia cells. IC50: 1.1 and 2.9 μM, respectively.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
EML 425; MolPort-042-624-542; BDBM50081125; AKOS027470241; 1,3-dibenzyl-5-[(4-hydroxy-2,6-dimethylphenyl)methylidene]-1,3-diazinane-2,4,6-trione
Solubility:
DMSO: 100 mM
Storage:
Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
MSDS:
Inquire
Quality Standard:
In-house standard
Quantity:
Milligram-Grams
InChIKey:
LUGQBJDYUPNAQQ-UHFFFAOYSA-N
InChI:
InChI=1S/C27H24N2O4/c1-18-13-22(30)14-19(2)23(18)15-24-25(31)28(16-20-9-5-3-6-10-20)27(33)29(26(24)32)17-21-11-7-4-8-12-21/h3-15,30H,16-17H2,1-2H3
Canonical SMILES:
CC1=CC(=CC(=C1C=C2C(=O)N(C(=O)N(C2=O)CC3=CC=CC=C3)CC4=CC=CC=C4)C)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 53963-43-2 Ginsenoside F1

Ginsenoside F1
(CAS: 53963-43-2)

Ginsenoside F1, a metabolite of ginsenoside Rg1, which is used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory activity.

CAS 22888-70-6 Silibinin

Silibinin
(CAS: 22888-70-6)

Silibinin (INN), also known as silybin, is the major active constituent of silymarin, standardized extract of the milk thistle seeds, containing mixture of flav...

CAS 481-72-1 Aloe-emodin

Aloe-emodin
(CAS: 481-72-1)

Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.

CAS 1005491-05-3 Tirasemtiv

Tirasemtiv
(CAS: 1005491-05-3)

Tirasemtiv is a a small-molecule fast-skeletal-troponin activator, which is being developed as a potential treatment for diseases and conditions associated with...

CAS 313380-27-7 FDI 6

FDI 6
(CAS: 313380-27-7)

FDI 6 is an inhibitor of the Forkhead box protein M1 transcription factor (FOXM1) (IC50 value 22.5 µM) that suppresses FOXM1 binding to DNA. FDI6 displaces ​FOX...

CAS 68497-62-1 Pramiracetam

Pramiracetam
(CAS: 68497-62-1)

Pramiracetam is a central nervous system stimulant and nootropic agent belonging to the racetam family of drugs. It is a more potent nootropic drug derived from...

CB 3703
(CAS: 32093-09-7)

CB 3703 is an inhibitor of hydrofolate reductase.

CAS 17008-69-4 Pseudobufarenogin

Pseudobufarenogin
(CAS: 17008-69-4)

Pseudobufarenogin is a natural compound extracted from toad species with unknown details.

FR-186054
(CAS: 179053-90-8)

FR-186054, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hyperlipidaemia.

CAS 163269-30-5 Bethoxazin

Bethoxazin
(CAS: 163269-30-5)

Bethoxazin(Bethoguard) is a new broad spectrum industrial microbicide with applications in material and coating preservation.

CAS 144092-28-4 Xenin

Xenin
(CAS: 144092-28-4)

Xenin, a 25-amino acid peptide initially isolated from human gastric mucosa, has 6 C-terminal amino acids in common with amphibian xenopsin. Xenin may stimulate...

CAS 2920-86-7 Prednisolone hemisuccinate

Prednisolone hemisuccinate
(CAS: 2920-86-7)

Prednisolone hemisuccinate is a metabolite of a derivative of cortisol called Prednisolone. It can be used to treat a variety of inflammatory and auto-immune co...

CAS 1465248-60-5 SPL-B

SPL-B
(CAS: 1465248-60-5)

SPL-B is an orally active inhibitor of transforming acidic coiled-coil protein (TACC3) exhibiting an inhibitory effect against the nucleation of centrosome micr...

PYR-7911
(CAS: 124307-91-1)

PYR-791 is an important synthetic intermediate for a lot of bio-active molecules, including porphyrins, bile pigments, photosensitizers, anticancer agents.

CAS 80-77-3 Chlormezanone

Chlormezanone
(CAS: 80-77-3)

Chlormezanone, a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.

CAS 548-83-4 Galangin

Galangin
(CAS: 548-83-4)

Galangin is a flavonoid naturally found in herbs acts as an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.

WRR483
(CAS: 1076088-50-0)

WRR483 is a potent and selective cysteine protease inhibitor with trypanocidal activity in cell culture and animal model. It is an analogue of K-11777. It demon...

D-Melphalan
(CAS: 13045-94-8)

D-Melphalan is an isomer of melphalan. Melphalan is Alkylating agent and DNA synthesis inhibitor using for the treatment of Multiple myeloma.

CAS 519-37-9 Etofylline

Etofylline
(CAS: 519-37-9)

β-hydroxyethyltheophylline is an inhibitor of 3’,5’-Cyclic Nucleotide Phosphodiesterase.

CAS 1465017-87-1 UPF-648 sodium salt

UPF-648 sodium salt
(CAS: 1465017-87-1)

UPF-648 sodium salt is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ± 10% KMO inhibition); ineffective at bloc...

Quick Inquiry

Verification code

Featured Items