|Description||Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.|
Exherin trifluoroacetate is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities, which selectively...
Botanical Source from Bufo bufo gargarizans and Bufo formosus, used for microbial transformation.
RVX297 is a BD2 selective inhibitor of BET bromodomains. It is structurally related to the clinical compound RVX-208. It has significant implications on differe...
N-Acetyl-β-Asp-Glu is a peptide neurotransmitter and the third-most-prevalent neurotransmitter in the mammalian nervous system.
Prim-O-glucosylcimifugin is a natural product extracted from the root of Saposhnikovia divaricata (Turcz.) Schischk. It can inhibit the proliferation of SMC(smo...
Glafenine hydrochloride, an anthranilic acid derivative, is a non-narcotic analgesic and non-steroidal anti-inflammatory drug. It is an ABCG2 inhibitor (IC50= 3...
BMS 433771 is a potent inhibitor of RSV replication in vitro with an average EC of 20nM
Neuropathiazol is a synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. It selectively induces neuronal...
OT-R antagonist 1
OT-R antagonist 1 is a nonpeptide OT-R antagonist, inhibitis IP3-Synthesis, rat OT-R (IC50 = 8 nM).
Cardamonin is a naturally occuring chalcone initially isolated from the seeds of Amomum subulatum and subsequently from other zingiberous plant species. Cardamo...
BMS-554417 is a novel inhibitor of IGF-IR, which inhibits IGF-IR and insulin receptor kinase activity and proliferation in vitro, with the IC50 for proliferatio...
UK 34787 is a thromboxane inhibitor，but no detailed information has been published yet.
1-methyl-7-nitroisatoic anhydride is a reagent which could detect local nucleotide flexibility. It is the most useful reagents for probing 2-hydroxyl reactivity...
β-Apo-13-carotenone, also known as D'Orenone, a naturally occurring β-apocarotenoid, is an antagonist of RXRα.
UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor (IC50= 0.48 nM) with selectivity against DPP-9, DPP-8 and DP...
Valrubicin (AD-32) is a chemotherapy drug used to treat bladder cancer. It is a semisynthetic analog of the anthracycline doxorubicin, and is administered by in...
Oct4 is a transcription factor which is involved in the reprogramming of somatic cells to produce pluripotent stem cells.
GNE-3500 has been found to be a Retinoic acid receptor-related Orphan receptor C agonist that could be probably significant in studies of some inflammatory dise...
Dixanthogen is the dominant species of xanthate adsorption on pyrite used as an ectoparasiticide.
PKR-IN-2 is a pyruvate kinase (PKR) activator. IC50: PKR (R510Q) ＜100 nM