|Description||Elsibucol, a metabolically stable derivative of probucol, inhibits atherosclerosis and preserves endothelial healing following arterial injury. In vitro, elsibucol reduces vascular smooth muscle cell proliferation without affecting cell viability.|
|Synonyms||4-[2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenoxy]butanoic acid; (4,2,6-di-tert-butyl-4-(1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl)-phenoxy-butyric acid); AGI-1096; elsibucol|
RPI-1 is a cell-permeable, ATP-dependent RET kinase inhibitor. Oral treatment with RPI-1 caused growth arrest or regression in 81% treated tumors. It can also b...
Cefovecin Sodium is an antibiotic of the cephalosporin class. It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphy...
JNJ 42396302 is an Antipsychotics originated by Janssen-Cilag. But no development has been reported yet.
Zinc undecylenate is a ungistatic fatty acid used in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
SV40 large T antigen NLS, a hexamer protein generated from Large T antigen residue 47 to 55, enables protein import into cell nucleus.
Meseclazone, a nonsteroidal anti-inflammatory drug (NSAID), exhibits inhibitory potency of secondary phase ADP aggregation.
BMS-188494 is the prodrug of BMS-187745, a squalene synthase inhibitor used as an anticholesterol drug.
Collagen proline hydroxylase inhibitor
Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor; useful for antifibroproliferative agents.
Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources.
Speract, a peptide associated with eggs of sea urchin, Lytechinus pictus, regulates sperm motility, also stimulates sperm mitochondrial metabolism.
Ropidoxuridine is a novel, orally available 5-substituted 2-pyrimidinone-2'-deoxyribonucleoside analogue and prodrug of 5-iododeoxyuridine (IUdR). It has radios...
Dihydrochelerythrine is a natural compound isolated from the leaves of Macleaya microcarpa, which has antifungal activity.
Acroteben is a bio-active chemical but no detailed information has been published yet.
Tafenoquine is an oral active and an 8-aminoquinoline antimalaria drug. It is being investigated as a potential treatment for malaria, as well as for malaria pr...
Isopropylantipyrinum is a derivative of phenazone with similar analgesic and antipyretic effects.
APC-366, an amino acid derivative, has been found to be a mast cell tryptase inhibitor and was once studied against asthma by Celera Genomics Group. Ki: 7.1 μM.
PD 131628 is a new fluoroquinolone as the bioactive form of PD 131112 which is a antibacterial agent originated by Pfizer. PD 131112 can be used for the treatme...
Prednisolone Acetate is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.
The brominated anilinoquinazoline derivative PD153035 exhibits a very high affinity and selectivity for the epidermal growth factor receptor tyrosine kinase (EG...
PACAP 6-38 is a PACAP (pituitary adenylate cyclase-activating polypeptide) non-stimulating competitive antagonist (IC50= 2 nM), with antitumor activity in vivo....