Elesclomol - CAS 488832-69-5
Catalog number:
B0084-212109
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
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Targets:
Apoptosis Inducer
Description:
Elesclomol is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative stress beyond baseline levels elevates ROS beyond sustainable levels, exhausting tumor cell antioxidant capacity, which may result in the induction of the mitochondrial apoptosis pathway. Normal cells are spared because the increase in the level of oxidative stress induced by this agent is below the threshold at which apoptosis is induced. Elesclomol is currently developed by Synta Pharmaceuticals Corp.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-212109 25 mg $198 In stock
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Synonyms:
STA-4783, Elesclomol
MSDS:
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Current Developer:
Synta Pharmaceuticals Corp.
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CAS 488832-69-5 Elesclomol

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