Elacestrant S enantiomer
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C30H38N2O2
Molecular Weight:
458.63
COA:
Inquire
Targets:
Estrogen Receptor/ERR
Description:
Elacestrant S enantiomer is an low activity enantiomer of Elacestrant. Elacestrant, also known as RAD1901, is a selective and orally
bioavailable small-molecule SERD (IC50= 48 and 870 nM for ERα and ERβ, respectively).
Brife Description:
A selective and orally available estrogen receptor (ERR) degrader
Synonyms:
(6S)-6-[2-[ethyl-[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-ol; Elacestrant (S enantiomer); ER-306323
Solubility:
DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Density:
1.111±0.06 g/cm3
InChIKey:
SIFNOOUKXBRGGB-SANMLTNESA-N
InChI:
1S/C30H38N2O2/c1-4-31-17-16-22-6-8-23(9-7-22)21-32(5-2)30-20-28(34-3)14-15-29(30)26-11-10-25-19-27(33)13-12-24(25)18-26/h6-9,12-15,19-20,26,31,33H,4-5,10-11,16-18,21H2,1-3H3/t26-/m0/s1
Canonical SMILES:
CCNCCC1=CC=C(C=C1)CN(CC)C2=C(C=CC(=C2)OC)C3CCC4=C(C3)C=CC(=C4)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Estrogen Receptor/ERR Products


CAS 77599-17-8 Panomifene

Panomifene
(CAS: 77599-17-8)

Panomifene is an Estrogen receptor antagonist under the development of Egis Pharmaceuticals. Phase II clinical trials for the treatment of breast cancer was dis...

CAS 182133-25-1 Arzoxifene

Arzoxifene
(CAS: 182133-25-1)

Arzoxifene, also known as LY353381, a synthetic aromatic derivative with anti-estrogenic properties, displays greater bioavailability and higher anti-estrogenic...

CAS 444643-64-5 CHF-4227

CHF-4227
(CAS: 444643-64-5)

CHF-4227 is a selective estrogen receptor modulator, binds with high affinity to the human estrogen receptor-alpha and -beta (dissociation constant K(i) = 0.017...

CAS 1853279-29-4 ZB716

ZB716
(CAS: 1853279-29-4)

ZB716 is a steroidal and orally bioactive selective estrogen receptor downregulator (SERD) with antiestrogenic activity. In both tamoxifen-naive and tamoxifen-r...

CAS 434-03-7 Ethisterone

Ethisterone
(CAS: 434-03-7)

Ethisterone is a progestogen hormone being considered to treat prostate cancer.It was the first orally-active progestin.

CAS 151555-47-4 RU 58668

RU 58668
(CAS: 151555-47-4)

RU 58668 is a pure antiestrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM). It has been shown to display potent antiproliferative activity...

CAS 72-33-3 Mestranol

Mestranol
(CAS: 72-33-3)

Mestranol is the 3-methyl ether of ethinylestradiol. It was the estrogen used in many of the first oral contraceptives.

CAS 50-28-2 Estradiol

Estradiol
(CAS: 50-28-2)

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is essential for the maintenance of fert...

CAS 177583-70-9 ZK 164015

ZK 164015
(CAS: 177583-70-9)

ZK 164015 is a potent estrogen receptor (ER) silent antagonist. ZK 164015 inhibits 17β-estradiol stimulation of luciferase activity (IC50 = 0.025 μM), and inhib...

CAS 198481-33-3 Bazedoxifene acetate

Bazedoxifene acetate
(CAS: 198481-33-3)

Bazedoxifene acetate, also called as TSE424 or WAY-140424, with antiosteoporotic it is a selective nonsteroidal estrogen receptor modulator (SERM) (ERα: IC50= 2...

CAS 805239-56-9 PHTPP

PHTPP
(CAS: 805239-56-9)

PHTPP, a pyrazolo[1,5-α]pyrimidine-based ligand, is a selective estrogen ERβ receptor antagonist that displays 36-fold selectivity over ERα. This compound has b...

CAS 1428-67-7 Diarylpropionitrile

Diarylpropionitrile
(CAS: 1428-67-7)

Diarylpropionitrile, also called as DPN, is a selective agonist of estrogen receptor β (ERβ) with a 70-fold higher relative binding affinity for ERβ(18%) versus...

CAS 26538-44-3 α-Zearalanol

α-Zearalanol
(CAS: 26538-44-3)

α-Zearalanol, derived from fungi in the Fusarium family, is a non-steroidal estrogen agonist that increases cancer cell proliferation in already existing breast...

CAS 15690-57-0 trans-Clomiphene

trans-Clomiphene
(CAS: 15690-57-0)

Trans-Clomiphene, a stilbenes derivative, has been found to be an estrogen receptor antagonist as well as testosterone agonist. It has been developed for hypogo...

CAS 68047-06-3 (Z)-4-Hydroxytamoxifen

(Z)-4-Hydroxytamoxifen
(CAS: 68047-06-3)

(Z)-4-Hydroxytamoxifen is a metabolite of Tamoxifen and acts as an estrogen receptor antagonist. It exhibits more than 100-fold affinity over Tamoxifen. (Z)-4-H...

CAS 524047-78-7 (R)-DPN

(R)-DPN
(CAS: 524047-78-7)

(R)-DPN has been found to be an estrogen receptor (ER) β agonist with higher affinity for estrogen receptor.

CAS 722533-56-4 Elacestrant

Elacestrant
(CAS: 722533-56-4)

Elacestrant, also referred to RAD1901, is a selective and orally available estrogen receptor (ERR) degrader (IC50= 48 and 870 nM for ERα and ERβ, respectively) ...

CAS 89778-27-8 Toremifene citrate

Toremifene citrate
(CAS: 89778-27-8)

Toremifene citrate is a selective estrogen receptor modulator (SERM) that binds to estrogen receptors to inhibit the estrogen activity.

CAS 1197194-61-8 Endoxifen E-isomer hydrochloride

Endoxifen E-isomer hydrochloride
(CAS: 1197194-61-8)

The hydrochloride salt form of E-isomer of Endoxifen which is a significant metamolite of Tamoxifen, could be a regulator of estrogen receptor and could be effe...

CAS 56632-39-4 BHPI

BHPI
(CAS: 56632-39-4)

BHPI is an antagonist of estrogen receptor α (ERα), for it elicits sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor.

Chemical Structure

CAS  Elacestrant S enantiomer

Quick Inquiry

Verification code

Featured Items