|Description||EL102, a HIF1α inhibitor, has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. IC50: 20-40 nM.|
|Synonyms||EL 102; EL102|
|Application||EL102 is a HIF1α inhibitor that has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
A derivative of psoralen, which intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks.
AM-206 is a bio-active chemical but no detailed data has been published yet.
Antipyrine is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic.
LY 249933 is a bio-active molecular under the development of Eli Lilly. It has positive inotropic activity as a cardioselective 1,4-dihydropyridine compound.
Ocaphane Hydrochloride is a strong antitumor agent used on a number of animal tumors such as Brown-Pearce carcinoma but is fairly toxic to hemopoietic organs.
Tranexamic Acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.
CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma.
Norelgestromin is a metabolite of Norgestimate which is a steroidal progestin.
4-Methylbenzylidene camphor (4-MBC) is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, speci...
p53 and MDM2 proteins-interaction-inhibi
p53 and MDM2 proteins-interaction-inhibitor racemic is an inhibitor of the interaction between p53 and MDM2 proteins.
Galangin is a flavonoid naturally found in herbs acts as an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.
Diperodon hydrochloride is a local anaesthetics designated by chemical abstracts as 3-piperidino-1,2-propanediol dicarbanilate monohydrate.
D-Glucosamine hydrochloride is present in mucopolysaccharides and in polysaccharides found in bacteria, fungi, higher plants has been used as a standard to quan...
Bleomycin sulfate is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin sulfate ...
Oroxylin A possessed abilities of inhibiting the ATRA-induced IL-6 production via modulation of LAP/LIP/CHOP in leukemia cell lines, which could providing a the...
Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the...
Astragaloside III is a saponin found in the root of Astragalus membranaceus (Fisch.) Bunge, which is known as huáng qí in Traditional Chinese Medicine. It has c...
Notoginsenoside R1 is extracted from the roots of Panax notoginseng (Burk.)F.H.Chen. It has some neuronal protective, antihypertensive effects and exhibits anti...
Daminozide is a highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A with IC50 values of 1.5, 0.55, and 2.1...
Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic. It is used for treatment of Dermatitis herpetiformis