|Description||EGLU is a group II mGluR antagonist and also a selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord.|
|Brife Description||group II mGluR antagonist|
|Purity||≥95% by HPLC|
|Synonyms||(2S)-α-Ethylglutamic acid; (2S)-2-amino-2-ethylpentanedioic acid|
EGLU is a group II mGluR antagonist and also a selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neon...
The hydrochloride salt form of ACDPP, which has been found to be a mGluR-5 antagonist.
YM 230888 is a selective mGlu1 antagonist (Ki = 13 nM) that inhibits mGlu1-mediated inositol phosphate production in rat cerebellar granule cells (IC50 = 13 nM)...
(RS)-MCPG Disodium Salt
(RS)-MCPG disodium salt is a non-selective group I/II metabotropic glutamate receptor antagonist.
LY 367385 is a selective mGlu1a receptor antagonist with an IC50 value of 8.8 μM for blockade of quisqualate-induced phosphoinositide hydrolysis. LY 367385 is u...
NPS 2390 is a Group I mGlu antagonist. NPS 2390 acts as a noncompetitive antagonist of mGluR1 and mGluR5 with IC50 values of 5.2 and 82 nM.
Spaglumic acid is the most abundant peptide neurotransmitter in the mammalian CNS. Spaglumic acid is a weak activator of NMDA receptors and a highly selective a...
Dipraglurant is a mGlu5 receptor negative allosteric modulator. It is currently in phase II for the treatment of dyskinesia in Parkinson's disease.