|Description||EGF816, also called as Nazartinib, a covalent mutant-selective EGFR inhibitor and potently inhibits the T790M resistance mutation while sparing wild-type EGFR. in vivo: demonstrated strong tumor regressions in several EGFR activating and resistant tumor m|
|Synonyms||N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide EGF816 UNII-KE7K32EME8 KE7K32EME8 EGF-816 1508250-71-2 GTPL9204 SCHEMBL16767232 SCHEMBL16767240 EGF 816 compound 47 [PMID: 27433829]|
|Solubility||Soluble in DMSO|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -45℃ for long term (months to years).|
|Shelf Life||2 years|
AG 18 (10 μM) inhibits EGF-induced proliferation of GH3 cells.
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