EGCG - CAS 989-51-5
Catalog number:
989-51-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H18O11
Molecular Weight:
458.37
COA:
Inquire
Targets:
Amyloid-β | Apoptosis Inducer | β-secretase
Description:
EGCG, also called Epigallocatechin gallate, under the IUPAC name [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, an antioxidant extracted from green tea, reduces Aβ42-induced cell death in three different cell types and inhibits β-secretase (IC50 = 1.6 μM).
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Brife Description:
Inhibits formation of amyloid fibrils; Inhibits β-secretase (IC50 = 1.6 μM)
Appearance:
White solid
Synonyms:
EGCG cpd; epigallo-catechin gallate; epigallocatechin gallate; epigallocatechin-3-gallate; epigallocatechin-3-O-gallate; EGCG; 989-51-5; Tea catechin; Teavigo; Catechin deriv.; (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate; (-)-EGCG; CCRIS 3729; CHEBI:4806; CHEMBL297453; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate; MFCD00075940; DSSTox_CID_567; DSSTox_RID_78830; DSSTox_GSID_29889; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate; (-)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate; polyphenols; Sunphenon; C22H18O11; (-)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate; (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol-3-(3,4,5-trihydroxybenzoate); CAS-989-51-5; SMR000449288; (− )-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate; C09731; W-5069; I14-7747; Q-100914; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxyb enzoate; [5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 2,3,4-trihydroxybenzoate; (-)-cis-3,4-Dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-1(2H)-benzopyran-3-yl Gallate; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate; (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl-3,4,5-trihydroxybenzoate; 3,4-Dihydro-5,7-dihydroxy-2R-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3R-yl-3,4,5-trihydroxybenzoate; 863-65-0; Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester; Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2R-cis)-; Teavigo; 2kdh; 3oob
Solubility:
Soluble to 10 mM in water and to 100 mM in ethanol
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -54℃ for long term (months to years).
MSDS:
Inquire
Boiling Point:
909.1°C at 760 mmHg
Density:
1.9 g/cm3
InChIKey:
WMBWREPUVVBILR-WIYYLYMNSA-N
InChI:
1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
Canonical SMILES:
C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 989-51-5 EGCG

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