Edonentan - CAS 210891-04-6
Catalog number:
210891-04-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C28H32N4O5S
Molecular Weight:
536.64
COA:
Inquire
Targets:
Endothelin Receptor
Description:
Edonentan, also known as BMS-207940, is a very potent and selective ETA endothelin receptor antagonist (Ki= 10 pM) that shows 80000-fold selective for ETA vs ETB.
Publictions citing BOC Sciences Products
  • >> More
Purity:
95%
Appearance:
Solid powder
Synonyms:
N-[[2-[2-[(4,5-dimethyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N,3,3-trimethylbutanamide; Edonentan; UNII-S5016F5ZH4 ;CHEMBL383581; 210891-04-6; UNII-2CCC8CH216; Edonentan[INN]; 210891-04-6 (Edonentan); 264609-13-4 (Edonentan hydrate)
MSDS:
Inquire
Quantity:
Data not available, please inquire.
InChIKey:
ORJRYNKVKJAJPY-UHFFFAOYSA-N
InChI:
InChI=1S/C28H32N4O5S/c1-18-19(2)37-30-26(18)31-38(34,35)24-10-8-7-9-23(24)22-12-11-20(27-29-13-14-36-27)15-21(22)17-32(6)25(33)16-28(3,4)5/h7-15H,16-17H2,1-6H3,(H,30,31)
Canonical SMILES:
CC1=C(ON=C1NS(=O)(=O)C2=CC=CC=C2C3=C(C=C(C=C3)C4=NC=CO4)CN(C)C(=O)CC(C)(C)C)C
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Endothelin Receptor Products


CAS 169545-27-1 IRL-2500

IRL-2500
(CAS: 169545-27-1)

IRL-2500, an indol derivative, has been found to be an endothelin B receptor antagonist that was once studied in hypertension.

CAS 210891-04-6 Edonentan

Edonentan
(CAS: 210891-04-6)

Edonentan, also known as BMS-207940, is a very potent and selective ETA endothelin receptor antagonist (Ki= 10 pM) that shows 80000-fold selective for ETA vs ET...

CAS 184036-34-8 Sitaxsentan

Sitaxsentan
(CAS: 184036-34-8)

Sitaxsentan, also called as IPI 1040 or TBC 11251, is a potent orally bioactive ET receptor antagonist that has a long duration of action (t1/2, 5–7 hours) and ...

RO462005
(CAS: 150725-87-4)

RO462005 is an endothelin receptor selective agonist.

CAS 156161-89-6 BQ 788 sodium salt

BQ 788 sodium salt
(CAS: 156161-89-6)

BQ 788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM) without significant activity on ETA receptor (IC50= 1300 nM).

Enrasentan
(CAS: 167256-08-8)

Enrasentan, an indene derivative, has been found to be an endothelin receptor antagonist that was once studied in reperfusion injury and heart failure therapy.

CAS 147536-97-8 Bosentan

Bosentan
(CAS: 147536-97-8)

Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

CAS 157380-72-8 TAK-044

TAK-044
(CAS: 157380-72-8)

Tak-044 has been found to be an endothelin receptor antagonist that was once studied against some sort of liver disorders and subarachnoid haemorrhage.

T-0201 Sodium
(CAS: 188307-16-6)

The sodium salt form of T-0201 which has been found to be an Endothelin A receptor antagonist that could be used as as anti-ischaemic agent and was once studied...

BMS-193884
(CAS: 176960-47-7)

BMS-193884, an oxazol derivative, has been found to be an endothelin A receptor antagonist and was once studied in the treatmen of heart failure.

Sparsentan
(CAS: 254740-64-2)

Sparsentan, also known as RE-021, BMS346567, is a dual antagonist of both angiotensin II and endothelin A receptor antagonist.

BMS 182874 Hydrochloride
(CAS: 1215703-04-0)

This active molecular is a selective non-peptide Endothelin ETA receptor antagonist. It displays more than 1000-fold selectivity over ETB receptors (Ki of 48 nM...

CAS 157212-55-0 Bosentan Hydrate

Bosentan Hydrate
(CAS: 157212-55-0)

Bosentan inhibits the presser response to big ET-1 both after i.v. and oral administration, with a long duration of action and no intrinsic agonist activity.

A-192621
(CAS: 195529-54-5)

A-192621 is a selective antagonist at endothelin ETB receptor with more effective than IRL-2500 in blocking IRL-1620-induced vasoconstriction, but both augmente...

CAS 173937-91-2 Atrasentan

Atrasentan
(CAS: 173937-91-2)

atrasentan hydrochloride is the orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective anta...

CAS 290815-26-8 Avosentan

Avosentan
(CAS: 290815-26-8)

Avosentan, also known as SPP301, R-639, and RO 67-0565, is a potent and selective endothelin receptor(ETA receptor) antagonist.

CAS 186497-07-4 Zibotentan (ZD4054)

Zibotentan (ZD4054)
(CAS: 186497-07-4)

Zibotentan (ZD4054)is an orally administered, potent and specific ETA-receptor (endothelin A receptor) antagonist (IC50 = 21 nM).

CAS 117399-94-7 Endothelin 1 swine, human

Endothelin 1 swine, human
(CAS: 117399-94-7)

Endothelin 1 (swine, human), a vasoconstrictor increased in plasma and explants of patients with uterine leiomyomas, is a synthetic peptide with the sequence of...

CAS 210421-74-2 Sitaxentan sodium

Sitaxentan sodium
(CAS: 210421-74-2)

Sitaxentan sodium inhibits ET-1-induced stimulation of phosphoinositide turnover with a Ki of 0.69 nM and a pA2 of 8.0.

CAS 441798-33-0 Macitentan

Macitentan
(CAS: 441798-33-0)

Macitentan is an orally available dual endothelin receptor (ETR) antagonist with potential antihypertensive and antineoplastic activity.

Chemical Structure

CAS 210891-04-6 Edonentan

Quick Inquiry

Verification code

Featured Items