|Description||Edasalonexent, also known as CAT-1004, is a NF-kappa B inhibitor under the development of Catabasis Pharmaceuticals and Sarepta Therapeutics. It is a Inflammation mediator inhibitor and could be an anti-inflammatory drug candidate. In Apr 2016, Phase-II clinical trials in Duchenne muscular dystrophy (In children) in USA were on-going. In Sep 2016, Catabasis Pharmaceuticals and Sarepta Therapeutics agreed to co-develop edasalonexent with an exon skipping treatment together in USA for Duchenne muscular dystrophy.|
|Synonyms||CAT-1004;Sodium salicylate-docosahexaenoic acid conjugate;N-(2-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido)ethyl)-2-hydroxybenzamide|
|Solubility||Soluble in DMSO|
|Application||Anti-inflammatory; Duchenne muscular dystrophy|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Current Developer||Catabasis Pharmaceuticals; Sarepta Therapeutics|
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