eCF309 - CAS 2001571-40-8
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C18H21N7O3
Molecular Weight:
383.4
COA:
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Targets:
PI3K
Description:
eCF309 is a potent and cell-permeable inhibitor of mTOR signaling (IC50 value 10 - 15 nM in vitro and in vivo) that exhibits >60-fold selectivity over PI3Ks. It is used as a highly valuable probe for chemical biology and biomedicine for its more potent activity compared to other mTOR inhibitors.
Brife Description:
mTOR signaling inhibitor
Purity:
98%
Synonyms:
5-[4-amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine; ECF 309; ECF-309; GTPL9571
MSDS:
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Application:
antitumor agent
InChIKey:
PSICWGWNIOOULV-UHFFFAOYSA-N
InChI:
InChI=1S/C18H21N7O3/c1-3-26-13(27-4-2)8-25-17-14(16(19)21-9-22-17)15(24-25)10-5-6-12-11(7-10)23-18(20)28-12/h5-7,9,13H,3-4,8H2,1-2H3,(H2,20,23)(H2,19,21,22)
Canonical SMILES:
CCOC(CN1C2=C(C(=N1)C3=CC4=C(C=C3)OC(=N4)N)C(=NC=N2)N)OCC
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CAS 2001571-40-8 eCF309

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