EC330 - CAS 2016795-77-8
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C30H32F2O2
Molecular Weight:
462.57
COA:
Inquire
Targets:
Others
Description:
EC330 is a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range, blocked formation of colonies in soft agar and inhibited angiogenesis (tube formation) in HUVEC cells. EC330 as a novel LIF inhibitor has targeted therapeutic perspectives for patients with aggressive primary tumors.
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Brife Description:
A leukemia inhibitory factor (LIF) inhibitor
Synonyms:
(8S,11R,13S,14S,17S)-11-(4-cyclopropylphenyl)-17-(1,1-difluoroprop-2-ynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Solubility:
10 mM in DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
623.4±55.0 ℃ at 760 Torr
Density:
1.26±0.1 g/cm3
InChIKey:
OWPPSPZDYGHPAN-GCNJZUOMSA-N
InChI:
1S/C30H32F2O2/c1-3-30(31,32)29(34)15-14-26-24-12-10-21-16-22(33)11-13-23(21)27(24)25(17-28(26,29)2)20-8-6-19(7-9-20)18-4-5-18/h1,6-9,16,18,24-26,34H,4-5,10-15,17H2,2H3/t24-,25+,26-,28-,29-/m0/s1
Canonical SMILES:
CC12CC(C3=C4CCC(=O)C=C4CCC3C1CCC2(C(C#C)(F)F)O)C5=CC=C(C=C5)C6CC6
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 2016795-77-8 EC330

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