|Description||EC330 is a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range, blocked formation of colonies in soft agar and inhibited angiogenesis (tube formation) in HUVEC cells. EC330 as a novel LIF inhibitor has targeted therapeutic perspectives for patients with aggressive primary tumors.|
|B0084-007323||5 mg||$298||In stock|
|Brife Description||A leukemia inhibitory factor (LIF) inhibitor|
|Solubility||10 mM in DMSO|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||623.4±55.0 ℃ at 760 Torr|
MMV390048 is a novel antimalarial compound and it can competitively inhibit the binding of only a single protein, P. falciparum PI4 kinase, to the beads. MV3900...
Isovaleramide is an anticonvulsant molecule isolated from Valeriana pavonii, it inhibits the liver alcohol dehydrogenases.
Gabexate mesylate is a serine protease inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation, and as a regiona...
Danshensu is an active component of Salvia miltiorrhiza that shows wide cardiovascular benefit. It suppresses the formation of reactive oxygen species and inhib...
Interferes with TLR4, TLR2/6 signaling; Orally active immunomodulatory agent; Inhibits TNF-α secretion via interference of macrophage TLR4 and TLR 2/6 signaling...
Benazepril is a drug of the angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure.
Sulfabenzamide is a widely used intermediate in many chemical areas and has been found to have antibacterial activity.
Ceranib 1 is a ceramidase inhibitor. It inhibits proliferation in SKOV3 ovarian carcinoma cells. It decreases sphingosine and sphingosine-1-phosphate (S1P) leve...
Pyridostatin pentahydrochloride binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM).
Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
Metyrapol, a dipyridine derivative, has been found to be a 11-deoxycorticosterone hydroxylation inhibitor and could always used as a medical diagnostic reagent ...
Verteporfin is a potent second-generation photosensitizing agent derived from porphyrin. It is used as a photosensitizer for photodynamic therapy to eliminate a...
UNC-926 is a methyl-lysine (Kme) reader domain inhibitor which binds to the MBT domain of L3MVTL protein (IC50= 3.9 μM).
Ornipressin Acetate, an analogue of Vasopressin, is used as a vasoconstrict or haemostatic and renal agent.
Meticrane, a sulphonamide derivative, is an effective diuretic and also an inhibitor of peripheral-type benzodiazepine receptor. IC50: 1 μM.
(±)-Epibatidine dihydrochloride is a highly potent nicotinic agonist used as a non-narcotic analgesic.
This bio-active molecular is a cell wall inhibitor as a antibacterial agent. LY 193239 has a lactam pyrazolidinone structure. Clinical trials for Bacterial infe...
WWL 113 is a carboxylesterase Ces3 and Ces1f inhibitor (IC50 = ~100 nM) with minimal activity against a panel of other serine hydrolases. WWL 113 was indicated ...
Isopropamide is a long-acting anticholinergic drug. It can be used for the treatment of peptic ulcers and other gastrointestinal disorders including hyperacidit...
Tinyatoxin is a neurotoxin, acting via vanilloid receptors of sensory nerves.