EC-17 - CAS 583037-91-6
Catalog number:
583037-91-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
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Description:
EC17, also known as Folate-FITC, is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, curculating anti-fluorescein antibodies.may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity.
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Appearance:
solid powder
Synonyms:
EC-17, EC17
MSDS:
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Current Developer:
Endocyte, Inc.
1.Cultural adaptation, validity, reliability and responsiveness of the Swedish version of the effective musculoskeletal consumer scale (EC-17).
Bremander A1, Wikström I, Larsson I, Bengtsson M, Hagel S, Strömbeck B. Musculoskeletal Care. 2012 Mar;10(1):43-50. doi: 10.1002/msc.1006. Epub 2012 Feb 2.
BACKGROUND: Endorsed by the Outcome MEasures in Rheumatoid Arthritis in Clinical Trials (OMERACT) group, The Effective Consumer Scale (EC-17) was developed in English for patients with musculoskeletal diseases to assess the skills and perceptions important for participating in and managing health care. The objective of this study was culturally to adapt the questionnaire into Swedish and to study its psychometric properties.
2.Translation, data quality, reliability, validity and responsiveness of the Norwegian version of the Effective Musculoskeletal Consumer Scale (EC-17).
Hamnes B1, Garratt A, Kjeken I, Kristjansson E, Hagen KB. BMC Musculoskelet Disord. 2010 Jan 29;11:21. doi: 10.1186/1471-2474-11-21.
BACKGROUND: The Effective Musculoskeletal Consumer Scale (EC-17) is a self-administered questionnaire for evaluating self-management interventions that empower and educate people with rheumatic conditions. The aim of the study was to translate and evaluate the Norwegian version of EC-17 against the necessary criteria for a patient-reported outcome measure, including responsiveness to change.
3.Translation and validation of the Dutch version of the Effective Consumer Scale (EC-17).
ten Klooster PM1, Taal E, Siemons L, Oostveen JC, Harmsen EJ, Tugwell PS, Rader T, Lyddiatt A, van de Laar MA. Qual Life Res. 2013 Mar;22(2):423-9. doi: 10.1007/s11136-012-0162-2. Epub 2012 Mar 28.
PURPOSE: The Effective Consumer Scale (EC-17) measures the skills of musculoskeletal patients in managing their own healthcare. The objectives of this study were to translate the EC-17 into Dutch and to further evaluate its psychometric properties.
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CAS 583037-91-6 EC-17

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