|Description||The brominated anilinoquinazoline derivative PD153035 exhibits a very high affinity and selectivity for the epidermal growth factor receptor tyrosine kinase (EGF-R TK) and shows a remarkable cytotoxicity against several types of tumor cell lines.|
Ajugol is an iridiod glucoside isolated from the roots of Rehmannia glutinosa.
L-690,330 is a potent inositol monophophatase (IMPase) inhibitor in vitro and in vivo. It induces autophagy in COS-7 cells independently of mTOR inhibition. It ...
A 350619 hydrochloride
A 350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC) that stimulates basal sGC and synergistically activates sGC in the presence of NO. It i...
Pyridostatin pentahydrochloride binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM).
Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12.
Pipazetate, as a cough suppressant, is a non-narcotic oral antitussive agent acting centrally on the medullary cough center.
Isothipendyl is a first generation H1 antagonist and anticholinergic for the topical treatment of itching associated with allergic reactions.
DZ2002 is a potent and reversible S-Adenosyl-L-homocysteine Hydrolase(SAHH; AdoHcy Hydrolase) inhibitor with Ki of 17.9 nM.
Pyraclonil is a herbicide agent.
Galanin (2-29) (rat)
Galanin (2-29) (rat) is a peptide agonist of galanin receptors displaying selectivity for GAL2 (Ki = 85, 1.9 and 12.6 nM at rat GAL1, GAL2 and GAL3 receptors, r...
Gly-Phe-Arg, a superpotent synthetic tripeptide, mimics the mud-crab pumping pheromone.
OT-R antagonist 2
OT-R antagonist 2 is a nonpeptide OT-R antagonist, inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM).
kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
Gap 19 is a selective connexin 43 (Cx43) hemichannel blocker displaying no effect on gap junction coupling or Panx-1 channels. Gap 19 decreases mitochondrial po...
Oxtriphylline is a cough medicine derived from xanthine used in the treatment for chronic asthma.
Cenerimod is an active Lysosphingolipid receptor agonist originated by Actelion Pharmaceuticals and EC50 value is 2.7 nM. It is a S1P1/EDG1 receptor agonist and...
(Arg)9, also known as Nona-L-arginine or Peptide R9, is a cell-permeable peptide used for drug delivery with neuroprotective activity (IC50= 0.78 μM in the glut...
TC-S 7006 is a potent, selective and reversible Tpl2 (Cot; MAP3K8) inhibitor (IC50 = 50 nM) with selectivity for Tpl2 over MEK, p38, Src, MK2, PKC and EGFR. TC-...
Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.
Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors.