|Description||The brominated anilinoquinazoline derivative PD153035 exhibits a very high affinity and selectivity for the epidermal growth factor receptor tyrosine kinase (EGF-R TK) and shows a remarkable cytotoxicity against several types of tumor cell lines.|
Ocaphane Hydrochloride is a strong antitumor agent used on a number of animal tumors such as Brown-Pearce carcinoma but is fairly toxic to hemopoietic organs.
Domiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant.
Mulberroside A, extracted from the root bark of white mulberry, could reduce P-gp expression and function being along with the activation of PKC and NF-κB. It h...
Trimethadione, an oxazolidinedione derivative, is an anticonvulsant commonly used in the treatment of epilepsy.
Rehmannioside A is an iridoid glucoside extracted from the roots of Rehmannia glutinosa.
1,2,2,6,6-Pentamethylpiperidine is a ganglion-blocking drug. It is one of the most strongly basic tertiary amine. It is ued as an oral treatment for hypertensio...
Tuftsin diacetate is a macrophage/microglial activator.
C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and ca...
unifiram (DM-235) is a piperazine derived research chemical which has nootropic effects in animal studies with significantly higher potency than piracetam.
Clonidine is an α2-Adrenergic agonist for neuropathic pain.
A novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.
Iopamidol is a nonionic, low-osmolar iodinated contrast agent, developed by Bracco.
Epothilone F, an active metabolite of Epothilone D, prevents cancer cells from dividing by interfering with tubulin.
CDy9, a pyrrolodiazaborinine derivative, has been found to be a fluorescent probe and could be used to detect and isolate intact stem cells.
Torsemide is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 ± 0.17 μM.
Gimeracil is a pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhib...
ARN-5187, a piperazin derivative, has been found to be a REV-ERBβ inhibitor that could induce apoptotic in cancer cells and probably be more effective in breast...
Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
CP-100829, an indole derivative, could probably be useful in some biological studies.
Lonidamine is a derivative of indazole-3-carboxylic acid, which for a long time, has been known to inhibit aerobic glycolysis in cancer cells. It seems to enhan...