|Description||(±)-E-Homocamptothecin is a potent topoisomerase I (Topo 1) inhibitor.|
|Brife Description||topoisomerase I (Topo 1) inhibitor|
|Synonyms||(+/-)-E-Homocamptothecin; BN-80245; BN 80245; BN80245; E-Homocamptothecin, (+/-)-|
Grepafloxacin is a quinoline antibacterial agent used to treat various bacterial infections.
Pirarubicin is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an ant...
Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively.
ABT-719, a fluoroquinolone derivative, has been found to be a DNA topoisomerase inhibitor that was once developed in antibacterial studies.
Clinafloxacin is a fluoroquinolone antibiotic with a broad-range of antibacterial activity. It inhibits both DNA gyrase and topoisomerase IV.
The mesylate salt form of alatrofloxacin, a fluoroquinolone derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed to be...
9-Aminocamptothecin is a water-insoluble camptothecin derivative and an inhibitor of the nuclear enzyme topoisomerase I, disrupting the repair of single-strand ...
Exatecan Mesylate (DX-8951) is a totally synthetic analogue of the topoisomerase I-inhibitor camptothecin, which was synthesised to impart increased aqueous sol...