|Description||Capsaicin, the major pungent ingredient found in hot red chili peppers of the genus Capsicum, suppresses the growth of several malignant cell lines.|
|Appearance||White to Off-White Solid|
|Synonyms||Capsaicinoids; Capsaicin; (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide;|
|Solubility||Soluble in DMSO|
|Storage||Store at -20 °C|
|Quality Standard||Enterprise Standard/CP|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
|Melting Point||67-69 °C|
|Current Developer||Alopecia Areata|
AMG8562 is a novel vanilloid receptor TRPV1 modulator.
MK-2295 is a potent TRPV1 antagonist. TRPV1 antagonists has the potential as analgesic and anti-inflammatory agents.
HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.
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Icilin is a synthetic CMR1/TRPM8 super agonist in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM) more potently than menthol or low temperatures.
Optovin is a reversible photoactive TRPA1 activator; stimulates human TRPA1 channels in vitro and enables repeated photoactivation of motor behaviors in wild-ty...
ABT 102 is a selective transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with IC50 values to be 5-7 nM. No recent reports of development iden...
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TCS 5861528 is a selective TRPA1 blocker with IC50 values are 14.3 and 18.7μM respectively), attenuates diabetes mellitus hypersensitivity and displays antinoci...
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PF-05105679 is a selective TRPM8 Antagonist with clinical efficacy in cold-related pain. IC50 value is 103 nM. It shows >100-fold selectivity for TRPM8 over a p...
Pyr6, a pyrazole derivative, is a selective inhibitor of ransient receptor potential cation 3 (TRPC3) channels that inhibited Orai1- and TRPC3-mediated Ca(2+) e...
SAR7334, a TRPC6 inhibitor, could be valuable in studying sorts of diseases related to TRPC.
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