|Description||Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects.It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.|
GR 79236, an effective Adenosine A1 receptor agonist, could probably be used as an anti-inflammatory agent. IC50: 3.1 nM(Ki).
Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects.It is used in the treatment of respiratory disorders like asthma, cardiac dyspne...
ASP-5854 is an adenosine A1 and A2A receptor antagonist receptor. It has therapeutic potential for the treatment of Parkinson's disease to ameliorate motor defi...
Capadenoson is a potent and selective adenosine A1 receptor agonist, which is a powerful protective mechanism in cerebral.
Sonedenoson is an adenosine A2 receptor agonist under the development of King Pharmaceuticals Research and Development. It can effectively promote rapid wound h...
LUF6000 is an allosteric modulator of the human A3 adenosine receptor (AR). It was found to be an allosteric enhancer of Emax. It exerted an Emax-enhancing effe...
N6-[2-(4-Aminophenyl)ethyl]adenosine is a potent, non-selective adenosine A3 adenosine receptor agonist. It could enhance the protective activity of carbamazepi...
KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors. The Ki values of KF21213 were 3.0 nM for the adenosine A2A receptors and >10,000 n...
CGS 21680, an A2 adenosine receptor selective agonist, has been found to be probably effective in inducing vasorelaxation and increasing in heart rate.
Preladenant is a potent as Adenosine A2 receptor antagonists.
CGS 21680 Hydrochloride
CGS 21680 Hcl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor.
PD-117519 is a N6-substituted adenosine receptor agonist. It shows oral antihypertensive activity in pharmacological animal models. It is used as a potential an...
N6-(2-Phenylethyl)adenosine is a selective A1 adenosine receptor agonist with anti-proliferative activity on bladder cancer cells.
KFM19 is a selective adenosine A1-antagonist with good bioavailability (IC50= 50 nM).
Regadenoson, as a coronary vasodilator it is a selective A2A adenosine receptor agonist in myocardial imaging.
412348 is an adenosine A2A receptor antagonist with anti-Parkinsonian activity in both rodent andprimate animal models. Because of its high affinity for the ade...
Trabodenoson is a selective adenosine A1 receptor agonist. Trabodenoson can significantly reduce IOP in glaucoma and OHT patients. Phase III clinical trials for...
FR-194921 is a potent, selective and orally active antagonist for central adenosine A1 receptors that displays high affinity and selectivity for the adenosine A...
N-0861 racemate is the racemate of N-0861 which appears to be an effective and selective A1 adenosine receptor antagonist in humans.
CF101 is a specific agonist to the A3 adenosine receptor, which inhibits the development of colon carcinoma growth in cell cultures and xenograft murine models...