Duvelisib R enantiomer - CAS 1261590-48-0
Catalog number:
1261590-48-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H17ClN6O
Molecular Weight:
416.86
COA:
Inquire
Targets:
PI3K
Description:
The R isomer analogue of Duvelisib which is a high selective PI3K δ/γ inhibitor.
Publictions citing BOC Sciences Products
  • >> More
Purity:
95%
Appearance:
Powder
Synonyms:
IPI-145 R enantiomer; IPI 145 R enantiomer; IPI145 R enantiomer; INK1197 R enantiomer; INK 1197 R enantiomer; INK-1197 R enantiomer
Solubility:
DMSO
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
The R isomer analogue of Duvelisib which is a high selective PI3K δ/γ inhibitor.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
SJVQHLPISAIATJ-CYBMUJFWSA-N
InChI:
InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m1/s1
Canonical SMILES:
CC(C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related PI3K Products


CAS 371935-74-9 PI-103

PI-103
(CAS: 371935-74-9)

PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α...

CAS 593960-11-3 PIK-93

PIK-93
(CAS: 593960-11-3)

PIK-93 is a potent PI3K inhibitor.

CAS 19870-46-3 1,3-Dicaffeoylquinic acid

1,3-Dicaffeoylquinic acid
(CAS: 19870-46-3)

1,3-Dicaffeoylquinic acid, a caffeoylquinic acid derivative found in artichoke, acts as an anti-hyperlipidemic agent and activates PI3K/Akt.

CAS 648450-29-7 AS-605240

AS-605240
(CAS: 648450-29-7)

AS605240 is a selective PI3Kgamma inhibitor, has been proved effective on several inflammatory diseases. Orally administration of AS605240 significantly prevent...

Leniolisib
(CAS: 1354690-24-6)

Leniolisib is a PI3K (phosphatidylinositol 3-kinase) inhibitor. No detailed information has been published yet.

CAS 1312445-63-8 NVP-BKM120 Hydrochloride

NVP-BKM120 Hydrochloride
(CAS: 1312445-63-8)

NVP-BKM120 Hcl(BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively.

AM-8508
(CAS: 1338483-67-2)

AM-8508 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-8508 exhibits good cellular potency (in vitro pAKT IC50 = 4.6 nM ) and excellen...

CAS 1431697-78-7 CAL-130 Hydrochloride

CAL-130 Hydrochloride
(CAS: 1431697-78-7)

In the absence of PTEN phosphatase tumor suppressor function, PI3Kγ or PI3Kδ alone can support leukemogenesis, whereas inactivation of both isoforms suppressed ...

CAS 371935-79-4 PI-103 Hydrochloride

PI-103 Hydrochloride
(CAS: 371935-79-4)

A selective class I PI3K inhibitor; it inhibits PI3K p110 isoforms, mTOC1 and also DNA-PK; a valuable tool compound

SAR-405
(CAS: 1523406-39-4)

SAR-405 is a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K) class III isoform Vps34 (IC50= 1.2 nM, Kd= 1.5 nM) without disrupting other PI3K...

copanlisib hydrochloride
(CAS: 1402152-13-9)

Copanlisib hydrochloride is a potent inhibitor of Class I phosphoinositide 3-kinase which showed a therapeutic effect on non-Hodgkin lymphoma. It was approved t...

AZD6482 (S-isomer)
(CAS: 1173900-37-2)

This active molecular is the S-configuration isomer of AZD6482. AZD6482 is a selective, ATP competitive PI3Kβ inhibitor and IC50 value is 0.01 μm. Meanwhile, AZ...

GSK2269557
(CAS: 1254036-71-9)

GSK2269557, an effective PI3K inhibitor, could be used as against inflammatory and some autoimmune diseases. It has just completes a phase II trial against Asth...

CAS 870281-82-6 CAL-101 (GS-1101)

CAL-101 (GS-1101)
(CAS: 870281-82-6)

Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL).

CAS 1013098-90-2 PI3Kα/mTOR-IN-1

PI3Kα/mTOR-IN-1
(CAS: 1013098-90-2)

PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR (Kis= 10.6 nM and 12.5 nM for mTOR and PI3Kα, respectively).

CAS 154447-36-6 LY294002

LY294002
(CAS: 154447-36-6)

LY294002 is a potent inhibitor of phosphoinositide PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively.

CAS 1627494-13-6 AZD8186

AZD8186
(CAS: 1627494-13-6)

AZD 8186 is a selective PI3Kβ/δ inhibitor (IC50= 0.003 μM for PI3Kβ, and 0.017 μM for PI3Kδ) with potential antineoplastic activity. It shows no significant bin...

GDC-0326
(CAS: 1282514-88-8)

GDC-0326 is a selective PI3Kα (α-Isoform of Phosphoinositide 3-Kinase) inhibitor. GDC-0326 is highly selective over other kinases. It has low plasma CL in human...

Seletalisib
(CAS: 1362850-20-1)

Seletalisib is a selective Phosphatidylinositol 3 kinase delta inhibitor originated by UCB.It is a Immunomodulator. Phaes I clinical trials for Plaque psoriasis...

CAS 1383716-40-2 Vps34-PIK-III

Vps34-PIK-III
(CAS: 1383716-40-2)

Vps34-PIK-III is a potent and selective inhibitor of the type 3 phosphatidylinositol 3-kinase (PI3K) vacuolar protein sorting 34 (Vps34) (IC50= 18 nM). Vps34-PI...

Quick Inquiry

Verification code

Featured Items