|Description||Duloxetine Hydrochloride is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).|
Fluoxetine is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
An antidepressant having effects on the autonomic nervous system; the drug is especially effective for mild and moderate depressions and a combination of Azaphe...
Escitalopram Oxalate also known by the brand names Lexapro and Cipralex among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) ...
Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. It is effective in inhibiting 5-ht uptake by blo...
Sertraline HCl is a 5-HT antagonist with Ki of 13 nM.
Trazodone, a phenylpiperazine compound, acts as a serotonin uptake inhibitor with antianxiety (anxiolytic) and sleep-inducing (hypnotic) effects.
Azaphen dihydrochloride monohydrate
Azaphen dihydrochloride monohydrate is a potent inhibitor of the reuptake of serotonin. It is a tricyclic antidepressant (TCA) approved in Russia for the treatm...
Duloxetine Hydrochloride is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anx...
Highly potent H1 histamine receptor antagonist (Kd = 310 pM) and tricyclic antidepressant. Also binds to the H4 histamine receptor (pKi = 6.79).
Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norep...
Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopa...
Paroxetine hydrochloride hemihydrate
Paroxetine hydrochloride hemihydrate is a antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs).
Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively. Milnacipran at hig...
Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram...
Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatmen...
Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively.
Fluvoxamine maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and sigma-1 receptor agonist.
Sibutramine hydrochloride monohydrate
A serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.
Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor.
class. It delays the reuptake of serotonin, resulting in serotonin persisting longer when it is released. It may also produce some of its effects via its weak 5...