Dropropizine - CAS 17692-31-8
Catalog number: 17692-31-8
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
Dropropizine is a racemic non-opiate antitussive agent, it is used as a cough suppressant.Dropropizine exhibits antitussive activity in cats noticeably lower than Pinacidil and Codeine.
UCB-1967; UCB 1967; UCB1967
Canonical SMILES:
1.Development and Validation of a Stability-Indicating LC-Method for the Simultaneous Estimation of Levodropropizine, Chloropheniramine, Methylparaben, Propylparaben, and Levodropropizine Impurities.
Kumar PA1, Raju TV, Thirupathi D, Kumar R, Shree J. Sci Pharm. 2013 Mar;81(1):139-50. doi: 10.3797/scipharm.1210-18. Epub 2012 Nov 17.
A simple, fast, and efficient RP-HPLC method has been developed and validated for the simultaneous estimation of Levodropropizine, Chloropheniramine, Methylparaben, Propylparaben, and the quantification of Levodropropizine impurities in the Reswas syrup dosage form. A gradient elution method was used for the separation of all the actives and Levodropropizine impurities by using the X-Bridge C18, 150 mm × 4.6 mm, 3.5 μm column with a flow rate of 1.0 mL/min and detector wavelength at 223 nm. The mobile phase consisted of a potassium dihydrogen orthophosphate buffer and acetonitrile. All the peaks were symmetrical and well-resolved (resolution was greater than 2.5 for any pair of components) with a shorter run time. The limit of detection for Levodropropizine and its Impurity B was 0.07 μg/ml & 0.05 μg/ml, whereas the limit of quantification was 0.19 μg/ml & 0.15 μg/ml respectively. The method was validated in terms of precision, accuracy, linearity, robustness, and specificity.
2.Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure.
Luo YL1, Li PB, Zhang CC, Zheng YF, Wang S, Nie YC, Zhang KJ, Su WW. Inflamm Res. 2013 Dec;62(12):1053-61. doi: 10.1007/s00011-013-0664-6. Epub 2013 Oct 2.
OBJECTIVE: The effects of four antitussives, including codeine phosphate (CP), moguisteine, levodropropizine (LVDP) and naringin, on airway neurogenic inflammation and enhanced cough were investigated in guinea pig model of chronic cough.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products

CAS 1225208-94-5 Cefiderocol

(CAS: 1225208-94-5)

This active molecular is a potent cephalosporin antibiotic with a catechol moiety on the 3-position side chain under the development of Shionogi. Cefiderocol ex...

ABT 38396
(CAS: 4853-98-9)

ABT 38396 is a synthetic bio-active chemical.

CAS 865783-95-5 ON-013100

(CAS: 865783-95-5)

ON-013100, a cell cycle inhibitor, altered the growth and cell cycle status of MCL lines and potently inhibited the expression of several important molecules, i...

(CAS: 1377239-83-2)

PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor. DprE1 is an essential enzyme involved in the cell wall biosynthesis of Corynebacterineae. The...

CAS 84687-43-4 Astragaloside IV

Astragaloside IV
(CAS: 84687-43-4)

Astragaloside IV has cardiovascular protective effects. It can protect the vascular endothelial cells. Meanwhile, it also have antiinflammatory and anti-virus e...

(CAS: 305821-96-9)

CP-472555 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in a...

CAS 143558-00-3 Rocuronium

(CAS: 143558-00-3)

Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.

CAS 79416-27-6 Methyl Aminolevulinate Hydrochloride

Methyl Aminolevulinate Hydrochloride
(CAS: 79416-27-6)

Methyl Aminolevulinate Hydrochloride is the methyl ester of Aminolevulinic Acid, which is a precursor of a photosensitizer and also is used as an add on agent f...

Chemical Structure

CAS 17692-31-8 Dropropizine

Quick Inquiry

Verification code

Featured Items