Doxazosin Mesylate - CAS 77883-43-3
Catalog number:
77883-43-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C24H29N5O8S
Molecular Weight:
547.58
COA:
Inquire
Targets:
Adrenergic Receptor
Description:
Doxazosin mesylate is an α1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia.
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Purity:
>98%
MSDS:
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1.Validation and utility of the PhysioTel™ Digital M11 telemetry implant for cardiovascular data evaluation in cynomolgus monkeys and Beagle dogs.
Cordes JS1, Heyen JR2, Volberg ML3, Poy N4, Kreuser S3, Shoieb AM3, Steidl-Nichols J3. J Pharmacol Toxicol Methods. 2016 May-Jun;79:72-9. doi: 10.1016/j.vascn.2016.01.006. Epub 2016 Feb 1.
INTRODUCTION: The cardiovascular liability of candidate compounds can be evaluated by a number of methods including implanted telemetry, jacketed telemetry and surface lead electrocardiogram (ECG). The utility of the new PhysioTel™ Digital M11 cardiovascular telemetry implant was evaluated in monkeys and dogs.
2.Relative cytotoxic potencies and cell death mechanisms of α1 -adrenoceptor antagonists in prostate cancer cell lines.
Forbes A1, Anoopkumar-Dukie S2, Chess-Williams R1, McDermott C1. Prostate. 2016 Feb 16. doi: 10.1002/pros.23167. [Epub ahead of print]
BACKGROUND: Some α1 -adrenoceptor antagonists possess anti-cancer actions that are independent of α1 -adrenoceptors and the aim of these studies was to assess the relative cytotoxic potencies of α1 -adrenoceptor antagonists and the mechanisms involved in these actions.
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CAS 77883-43-3 Doxazosin Mesylate

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