|Description||Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.|
|Synonyms||L671152; MK507; Trusopt|
Bisegliptin is an antidiabetic agent, but no detailed information has been published yet.
Sugammadex, a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periphery, is an agent for reversal of neuromuscular blockade by the agent rocu...
Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
iMDK is an inhibitor of midkine (MDK) expression, a growth factor commonly expressed in malignant tumors. iMDK dose-dependently inhibits MDK expression to atten...
GW6604 is a potent and selective ALK-5 inhibitor with an IC(50) of 140 nM and in a cellular assay inhibited TGF-beta-induced transcription of PAI-1 (IC(50): 500...
4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine, a nonpolar, essential amino acid that naturally occurs in the human body and is also used...
BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression.
GC376 is a 3CLpro inhibitor which is previously reported to be active against the 3CLpro of multiple coronaviruses, including SARS-CoV, but with highest potency...
Cgp 8716 is a major metabolite of GP53,633 which is a basic non-steroidal anti-inflammatory agent Originated by Novartis.
Dehydrocostus lactone and CL from root of S. lappa have anti-colorectal cancer activities through inhibiting Wnt/β-catenin pathway.
TOFA, also called as RMI14514 or MDL14514, is a cell-permeable, potent, reversible, and competitive allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA). TOF...
Fenoprofen calcium hydrate
Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).
FR-193262 is a designed prostacyclin mimetic without PG skeleton which exhibits potent PGI2 agonistic activity with good selectivity for IP receptor and bioavai...
Clofentezine is an active substance of plant protection product used as pesticide, acaricide. It belongs to the chemical family of quinoxalines. It is used in a...
Iopromide is a contrast medium produced by Bayer Healthcare. It is a low osmolar, non-ionic contrast agent for intravascular use. It can be used in radiographic...
Gynostemma Extract is a saponins extract derived from the Gynostemma pentaphyllum.
MK-142 is a bioactive agent with antiarrhythmic properties with its content in the skeletal muscles indicates a high affinity of the examined substance to the ...
Neridronic acid is a Bone resorption factor inhibitor and it can be used to treat Osteogenesis imperfecta and Paget's disease of bone.
Aminothiazole can be used as a thyroid inhibitor and it has antibacterial activity.