|Description||Domperidone is a medication developed by Janssen Pharmaceutica that acts as a peripherally-selective antagonist of the dopamine D2 and D3 receptors.|
Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist like other atypical antipsychotic agents. Ziprasidone targets dopamine neurotransmis...
Droperidol is a potent antagonist of dopamine subtype 2 receptors in the limbic system.
Nomifensine, also called as Hoe 984 or Linamiphen, as a norepinephrine-dopamine reuptake inhibitor it is an antidepressant drug but due to increased incidence o...
Zicronapine, an inden derivative, has been found to be neurotransmitter receptor modulators of sorts of neurotransmitter and was studied against Schizophrenia.
Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary...
Tiapride is a D2 and D3 dopamine receptor antagonist used to treat a variety of neurological and psychiatric disorders.
ABT670 is a drug which acts as a potent, superior orally bioavailable dopamine agonist selective for the D4 subtype. It was used as a possible treatment for ere...
Fenoldopam is a selective D1 receptor partial agonist, binds to α2-adrenoceptors, increasing renal blood flow used as an antihypertensive agent.
Vanoxerin is a dopamine uptake inhibitor. It is potentially used for the treatment of atrial fibrillation.
Dexpramipexole, also known as R-(+)-Pramipexole, is one of the impurities of pramipexole(USP D). It coule be used as a negative control in the research of dopam...
Amisulpride hydrochloride could inhibit radioligand binding to native dopamine D2 receptor in membranes from the rat striatum with an IC50 value of 21nM. It has...
Aplindore Fumarate is a partial agonist selective for the dopamine receptor D2 used in the therapeutic treatment of Parkinson Disease and restless legs syndrome...
The hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's dise...
Zuclopenthixol is an antagonist at D1 and D2 dopamine receptors. It also has high affinity for alpha1-adrenergic and 5-HT2 receptors, but it has weaker histamin...
Eticlopride is a selective dopamine D2 antagonist . It was initially developed as a potential antipsychotic agent. Now Eticlopride is primarily used in pharmaco...
PD-118717 is a putative piperazinyl benzopyranone dopamine autoreceptor(DA) agonist. It has the profile of a DA autoreceptor agonist in neurochemical and neurop...
Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM...
Cariprazine is an orally active D2/D3 dopamine receptor antagonist exhibits high selectivity and affinity to dopamine D3(Ki=0.09 nM) and D2 (Ki=0.5 nM) receptor...
Barnetil acts as a selective D2 and D3 receptor antagonist, which has high affinity for these receptors of dissociation constants of 2.2 nM and 2.4 nM respectiv...
Veralipride is a D2 receptor antagonist in the hypothalamic system and has a half-life of approximately 12 hours. Veralipride is highly active on the neurotrans...