DM4 - CAS 796073-69-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C38H54ClN3O10S
Molecular Weight:
780.37
COA:
Inquire
Targets:
Others
Description:
DM4, a chemical derivative of maytansine, is an intermediate used to prepare semisynthetic maytansine analogs which can be conjugated with antibodies for the targeted treatment of cancer.
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Brife Description:
A potent and selective cytotoxic agent
Synonyms:
(14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(4-mercapto-4-methylpentanoyl)-N-methyl-L-alaninate; Ravtansine; N2’-Deacetyl-N2’-(4-mercapto-4-methyl-1-oxopentyl)-maytansine
Solubility:
DMSO: 10 mM
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
943.2±65.0 ℃ at 760 Torr
Melting Point:
185-187 ℃ (decomp)
Density:
1.29±0.1 g/cm3
InChIKey:
JFCFGYGEYRIEBE-YVLHJLIDSA-N
InChI:
1S/C38H54ClN3O10S/c1-21-12-11-13-28(49-10)38(47)20-27(50-35(46)40-38)22(2)33-37(6,52-33)29(51-34(45)23(3)41(7)30(43)14-15-36(4,5)53)19-31(44)42(8)25-17-24(16-21)18-26(48-9)32(25)39/h11-13,17-18,22-23,27-29,33,47,53H,14-16,19-20H2,1-10H3,(H,40,46)/b13-11+,21-12+/t22-,23+,27+,28-,29+,33+,37+,38+/m1/s1
Canonical SMILES:
C/C(CC1=CC(OC)=C(Cl)C(N(C(C[C@]([C@]2(C)O[C@H]2[C@@H]3C)([H])OC([C@@H](N(C(CCC(C)(C)S)=O)C)C)=O)=O)C)=C1)=C\C=C\[C@@H](OC)[C@](NC4=O)(C[C@]3([H])O4)O
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Chemical Structure

CAS 796073-69-3 DM4

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