Disperse Yellow 54 - CAS 12223-85-7
Catalog number: 12223-85-7
Category: Intermediates
Molecular Formula:
C18H11NO3
Molecular Weight:
289.289
COA:
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Purity:
98%
Synonyms:
Disperse Yellow 3GE; Disperse Yellow E-3G; Disperse yellow 54 (C.I. 47020); Yellow E-2G
MSDS:
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Boiling Point:
502ºC at 760mmHg
Density:
1.435g/cm3
InChIKey:
FDTLQXNAPKJJAM-UHFFFAOYSA-N
InChI:
InChI=1S/C18H11NO3/c20-14-9-10-5-1-4-8-13(10)19-16(14)15-17(21)11-6-2-3-7-12(11)18(15)22/h1-9,15,20H
Canonical SMILES:
C1=CC=C2C(=C1)C=C(C(=N2)C3C(=O)C4=CC=CC=C4C3=O)O
1.Contact allergy from disperse dyes in textiles: a review.
Malinauskiene L1, Bruze M, Ryberg K, Zimerson E, Isaksson M. Contact Dermatitis. 2013 Feb;68(2):65-75. doi: 10.1111/cod.12001.
Several disperse dyes (DDs) are still considered to be the most important allergens in textile dermatitis, but there are sparse data about their current use in textiles. The aim of this review was to evaluate published studies and reports on contact allergy to DDs published in PubMed during the last 22 years (1990-2012). Prevalence data are provided by study and by dye, as well as by the described clinical peculiarities of DD dermatitis. We reviewed 54 studies. In total, 26 DDs were tested. The average prevalence in screening studies was >1% for Disperse Blue 106, Disperse Blue 124, and Disperse Orange 3. There is a lack of data on patch testing with Disperse Blue 26, Disperse Blue 102, Disperse Orange 37, Disperse Orange 149, Disperse Yellow 23 and Disperse Yellow 49, which are listed as allergens by the EU Commission. It is necessary to check the purity and identity of dyes used for patch testing, confirm the clinical relevance of positive reactions by patch testing with suspected textiles, and, if the results are positive, determine the culprit dye.
2.Contact allergy to textile dyes in southern Sweden.
Ryberg K1, Isaksson M, Gruvberger B, Hindsén M, Zimerson E, Bruze M. Contact Dermatitis. 2006 Jun;54(6):313-21.
Contact allergy to disperse dyes in textiles is documented in prevalence studies from southern Europe. To evaluate the prevalence of allergic patch test reactions to different textile dyes in southern Sweden, and to look at the sites of dermatitis in individuals hypersensitive to textile dyes, we retrospectively investigated 3325 consecutively patch-tested patients. They had all been patch tested with the standard test series supplemented with a textile dye mix (TDM) consisting of 8 disperse dyes, i.e. Disperse (D) Blue 35, 106 and 124, D Yellow 3, D Orange 1 and 3 and D Red 1 and 17. All but 3 of the TDM-positive patients were additionally tested with the separate dyes included in the mix. The frequency of contact allergy to TDM was 1.5%, which is comparable with studies from southern Europe. The most common dye allergen was D Orange 1. The high prevalence of allergic reactions to D Orange 1 was unexpected, whereas test reactions to D Blue 106 and 124 were lower than expected from other studies.
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CAS 12223-85-7 Disperse Yellow 54

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