Disodium (R)-2-Hydroxyglutarate - CAS 103404-90-6
Catalog number:
B0084-159285
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C5H6Na2O5
Molecular Weight:
192.08
COA:
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Targets:
α-ketoglutarate-dependent dioxygenases
Description:
Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Kiof 0.628 mM. In U-87MG cells, (R)-2-Hydroxyglutarate acts as weak antagonists of α-KG to inhibit α-KG-dependent histone demethylases and increases dimethylation on both H3K9 and H3K79.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-159285 100 mg $198 In stock
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Brife Description:
competitive inhibitor of α-ketoglutarate-dependent dioxygenases, antagonists of α-KG
Purity:
98%
Appearance:
Pale Orange Solid
Synonyms:
d-α-hydroxyglutaric acid disodium salt; (2R)-2-Hydroxyglutaric Acid Disodium Salt; D-alpha-Hydroxyglutaric acid (disodium salt)
Solubility:
Water, 38mg/mLwarmed(197.83mM);DMSO, <1mg/mL(<1mM);Ethanol, <1mg/mL(<1mM)
Storage:
3 years -20℃ powder; 6 months -80℃ in solvent
MSDS:
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Shelf Life:
2 years if stored properly
InChIKey:
DZHFTEDSQFPDPP-HWYNEVGZSA-L
InChI:
InChI=1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
Canonical SMILES:
C(CC(=O)[O-])C(C(=O)[O-])O.[Na+].[Na+]
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Chemical Structure

CAS 103404-90-6 Disodium (R)-2-Hydroxyglutarate

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