Diphenylpyraline hydrochloride - CAS 132-18-3
Catalog number: 132-18-3
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
Histamine Receptor
The hydrochloride salt form of Diphenylpyraline, one of the first-generation antihistamine agent, has been found to exhibit anticholinergic activity and could be used against Parkinson's disease.
White to off-white powder
H2O: > 36 mg/mL
-20ºC Freeze
The hydrochloride salt form of Diphenylpyraline is one of the first-generation antihistamine agent and has been found to exhibit anticholinergic activity and could be used against Parkinson's disease.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Melting Point:
203-205 °C
Canonical SMILES:
1.[Efficacy of compound Xuanju Capsule combined with apomorphine hydrochloride on erectile dysfunction].
Wang BQ1. Zhonghua Nan Ke Xue. 2012 Dec;18(12):1108-10.
OBJECTIVE: To investigate the clinical effect of Compound Xuanju Capsule combined with apomorphine hydrochloride on penile erectile dysfunction (ED).
2.Porous silicon-based direct hydrogen sulphide fuel cells.
Dzhafarov TD1, Yuksel SA. J Nanosci Nanotechnol. 2011 Oct;11(10):9012-5.
In this paper, the use of Au/porous silicon/Silicon Schottky type structure, as a direct hydrogen sulphide fuel cell is demonstrated. The porous silicon filled with hydrochlorid acid was developed as a proton conduction membrane. The Au/Porous Silicon/Silicon cells were fabricated by first creating the porous silicon layer in single-crystalline Si using the anodic etching under illumination and then deposition Au catalyst layer onto the porous silicon. Using 80 mM H2S solution as fuel the open circuit voltage of 0.4 V was obtained and maximum power density of 30 W/m2 at room temperature was achieved. These results demonstrate that the Au/Porous Silicon/Silicon direct hydrogen sulphide fuel cell which uses H2S:dH2O solution as fuel and operates at room temperature can be considered as the most promising type of low cost fuel cell for small power-supply units.
3.Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: An observational study in rats.
Richter T1, Bergmann R2, Pietzsch J2,3, Mueller MP1, Koch T1. Clin Hemorheol Microcirc. 2015 Jul 16;60(2):253-62. doi: 10.3233/CH-141867.
INTRODUCTION: Gastric aspiration events are recognized as a major cause of pneumonitis and the development of acute respiratory distress syndrome. The first peak in the inflammatory response has been observed one hour after acid-induced lung injury in rats. The spatial pulmonary blood flow (PBF) distribution after an acid aspiration event within this time frame has not been adequately studied. We determined therefore PBF pattern within the first hour after acid aspiration.
4.Penetration enhancement of lidocaine hydrochlorid by a novel chitosan coated elastic liposome for transdermal drug delivery.
Li L1, Zhang Y, Han S, Qu Z, Zhao J, Chen Y, Chen Z, Duan J, Pan Y, Tang X. J Biomed Nanotechnol. 2011 Oct;7(5):704-13.
An effective transdermal delivery system for local anaesthetic was developed with lidocaine hydrochloride (LID) as model drug. Chitosan coated elastic liposome (CCEL) were proposed and its in vitro/in vivo skin permeation properties were evaluated. Elastic liposome composed of soya lecithin with sodium deoxycholate (SDC) as edge activator, was prepared by rotary evaporation-sonication method. Chitosan (CH) (0.1-0.5%, w/v) coated elastic liposome by electrostatic attraction of negative elastic liposome and positive CH. CH coating changed the elastic liposome surface charge and increased the vesicle size. The drug encapsulation efficiency (EE) decreased with the increase of CH content. CH coated elastic liposome demonstrated an improved physicochemical stability at 4 degrees C in a 3 months storage period. After coated, CCEL displayed a prolonged drug release profile in vitro release study. The in vitro/in vivo studies showed that CCEL were able to give a statistically significant improvement of skin permeation of LID and significantly reduced pain in comparison with elastic liposome and CH solution.
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CAS 132-18-3 Diphenylpyraline hydrochloride

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