Dihydrotachysterol - CAS 67-96-9
Catalog number:
67-96-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C28H46O
Molecular Weight:
398.66
COA:
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Description:
Dihydrotachysterol is a vitamin D that can be regarded as a reduction product of vitamin D2 activated in the liver. It does not require renal hydroxylation like vitamin D2 and vitamin D3. It could stimulate intestinal calcium absorption and increases renal phosphate excretion. It is widely used for hypocalcemic hypoparathyroidism following surgical removal of parathyroids.
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Purity:
98%
Appearance:
White Solid
Synonyms:
7,22-trien-3-ol,(3-beta,5e,7e,10-alpha,22e)-10-secoergosta-5;Dichystrolum;Dihydrotachysterolum;Dihydral;(1S,3E,4S)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylcyc
Solubility:
Chloroform (Slightly), Methanol (Slightly)
Storage:
Amber Vial, -20˚C Freezer
MSDS:
Inquire
Application:
Dihydrotachysterol could stimulate intestinal calcium absorption and increases renal phosphate excretion. It is widely used for hypocalcemic hypoparathyroidism following surgical removal of parathyroids.
Quality Standard:
In-house standard
Quantity:
Grams to Kilograms
Boiling Point:
499.5±24.0 °C | Condition: Press: 760 Torr
Melting Point:
125-127 °C
Density:
1.003±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
ILYCWAKSDCYMBB-OPCMSESCSA-N
InChI:
InChI=1S/C28H46O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-22,25-27,29H,7-8,11,14-18H2,1-6H3/b10-9+,23-12+,24-13+/t20-,21-,22+,25-,26+,27-,28+/m0/s1
Canonical SMILES:
CC1CCC(CC1=CC=C2CCCC3(C2CCC3C(C)C=CC(C)C(C)C)C)O
1.Dihydrotachysterol intoxication treated with pamidronate: a case report.
Jensterle M1, Pfeifer M, Sever M, Kocjan T. Cases J. 2010 Mar 26;3:78. doi: 10.1186/1757-1626-3-78.
INTRODUCTION: Hypoparathyroidism is a chronic condition which requires a lifelong substitution with vitamin D analogues and careful monitoring. This is especially true for older patients and older compounds as dihydrotachysterol with longer half-life that might lead to long-lasting hypercalcemic episodes.
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CAS 67-96-9 Dihydrotachysterol

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