|Description||Dihydroartemisinin (DHA) is a semi-synthetic derivative of artemisinin and isolated from the traditional Chinese herb Artemisia annua.|
|Synonyms||SM-224, CGP 56696|
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)
FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM, 5-10 times lower than the IC50 of fatostatin (~10 μM).
Levetiracetam is an anticonvulsant medication used to treat epilepsy.
BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression.
Bendroflumethiazide is a thiazide diuretic as a Na++Cl- symport inhibitor. Bendroflumethiazide can be used in the treatment of mild heart failure although loop ...
BAY-876 is a potent and selective GLUT1 inhibitor (IC50 = 2 nM) with good stability in vitro and high bioavailability in vivo. BAY-876 can be used as an antican...
SMI 481 is a small-molecule inhibitor (SMI) of the yeast phosphatidylinositol transfer proteins (PITP) Sec14 (IC50 values of 211 nM and 2.87 μM for Sec14 mediat...
FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis i...
This active molecular is a scavenger receptor B1 antagonist under the development by iTherX Pharmaceuticals for the treatment of Hepatitis C. ITX-5061 shows a s...
DIBA, a benzamide derivative, has been found to be an ER zinc finger inhibitor that could be significant in studies of breast cancers.
13-Oxyingenol Dodecanoate is a derivative of Ingenol acts as a diterpene compound with antinematodal activity.
Simetryn, a methylthiotriazine derivative, is a herbicide which is commonly used in rice paddy. LC50: 16.9-3.70 mg/L (79.3-17.4 microM).
ADAMTS-5 (A Disintegrin And Metalloproteinase with ThromboSpondin motifs 5) is an aggrecanase-2. ADAMTS-5 is involved in the catabolism of aggrecan and collagen...
Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezi...
M2I-1 is a protein-protein interaction inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC.
Sodium Nitroprusside is a potent vasodilator working through releasing NO spontaneously in blood.
Ridogrel is a thromboxane synthase inhibitor used for the prevention of systemic thrombo-embolism. It is also a receptor antagonist that may be used as an adjun...
CP-744809 is a highly selective orally available small molecule inhibitor of aldose reductase.
Benzoylmesaconine is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis.
A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transf...