Dibenzylfluorescein - CAS 97744-44-0
Molecular Formula:
C34H24O5
Molecular Weight:
512.6
COA:
Inquire
Application\Fluorophore:
Fluorescent Enzyme Substrates
Description:
Dibenzylfluorescein is a fluorogenic probe that acts as a substrate for specific CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein produces fluorescein benzyl ether when dealkylated by these CYP isoforms, which is further hydrolyzed to fluorescein by the addition of base (typically 2 M NaOH). It is used for detecting changes in catalytic activity by medication or the onset of disease.
Purity:
≥98%
Appearance:
Orange Solid
Synonyms:
2-[3-oxo-6-(phenylmethoxy)-3H-xanthen-9-yl]-benzoic acid, phenylmethyl ester; DBF; O-Benzylfluorescein benzyl ester; Benzyl 2-[6-(benzyloxy)-3-oxo-3H-xanthen-9-yl]benzoate
Storage:
Store at -20°C
MSDS:
Inquire
Melting Point:
>179°C (dec.)
Excitation:
485 nm
Emission:
538 nm
InChIKey:
YZJGKSLPSGPFEV-UHFFFAOYSA-N
InChI:
InChI=1S/C34H24O5/c35-25-15-17-29-31(19-25)39-32-20-26(37-21-23-9-3-1-4-10-23)16-18-30(32)33(29)27-13-7-8-14-28(27)34(36)38-22-24-11-5-2-6-12-24/h1-20H,21-22H2
Canonical SMILES:
C1=CC=C(C=C1)COC2=CC3=C(C=C2)C(=C4C=CC(=O)C=C4O3)C5=CC=CC=C5C(=O)OCC6=CC=CC=C6
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Chemical Structure

CAS 97744-44-0 Dibenzylfluorescein

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