Diarylpropionitrile - CAS 1428-67-7
Catalog number:
1428-67-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H13NO2
Molecular Weight:
239.27
COA:
Inquire
Targets:
Estrogen Receptor/ERR
Description:
Diarylpropionitrile, also called as DPN, is a selective agonist of estrogen receptor β (ERβ) with a 70-fold higher relative binding affinity for ERβ(18%) versus ER (0.25%). ERβ: EC50 = 0.85 nM; ERα: EC50 = 66 nM
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Purity:
>99 %
Appearance:
White powder
Synonyms:
2,3-BIS(4-HYDROXYPHENYL)-PROPIONITRILE;DPN;2,3-bis(p-hydroxyphenyl)propionitrile;propionitrile,2,3-bis(p-hydroxyphenyl);2,3-Bis(4-hydroxyphenyl)propanenitrile;2,3-Bis(4-hydroxyphenyl)propiononitrile;Diarylpropionitrile
Solubility:
Soluble to 30 mM in 1eq. NaOH, to 100 mM in ethanol, to 100 mM in DMSO, to ~30 mg/ml in DMF, and to 0.5 mg/ml at 25 °C in water
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -37℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Density:
1.256 g/cm3
InChIKey:
GHZHWDWADLAOIQ-UHFFFAOYSA-N
InChI:
1S/C15H13NO2/c16-10-13(12-3-7-15(18)8-4-12)9-11-1-5-14(17)6-2-11/h1-8,13,17-18H,9H2
Canonical SMILES:
C1=CC(=CC=C1CC(C#N)C2=CC=C(C=C2)O)O
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