|Description||Dexrazoxane is a cardioprotective compound against anthracyclines. It is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.|
|Synonyms||Cardioxane; ICRF187; NSC169780; Zinecard; Totect; Savene|
NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility.
Ipfencarbazone is a non-hormonal translocation-type herbicide. It is thought to inhibit the biosynthesis of very long chain fatty acids in plants. Preparations ...
ML-390 is an inhibitor of human DHODH, which induces differentiation in acute myeloid leukemia cell lines U937 (murine) and THP-1 (human) cell lines with an EC5...
AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor and showed no inhibition or stimulation of >50% at 10μM in a standard selectivity panel of...
Speract, a peptide associated with eggs of sea urchin, Lytechinus pictus, regulates sperm motility, also stimulates sperm mitochondrial metabolism.
BMS 262084 is a potent and selective azetidinone-based beta-lactam tryptase inhibitor.
Meticrane, a sulphonamide derivative, is an effective diuretic and also an inhibitor of peripheral-type benzodiazepine receptor. IC50: 1 μM.
BPD-Ring B is a product from the synthesis of verteporfinin. It can be used for making porphyrin-related dye, nanoparticles, photosensitizers, and other photody...
Diapamide is a new diuretic and antihypertensive agent.
Imazapic, a 2-substituted imidazole derivative, is a selective herbicide which could be commonly used for the preand post-emergent control of some sorts of annu...
A2A inverse agonist; Also endogenous STING and DDX41 agonist
RPI-1 is a cell-permeable, ATP-dependent RET kinase inhibitor. Oral treatment with RPI-1 caused growth arrest or regression in 81% treated tumors. It can also b...
Quizalofop-P-ethyl, a quinoxaline derivative, is a sort of post-emergence herbicide that might be effective in regulating annual and perennial grass weeds.
Sulofenur is a diarylsulfonylurea with potential antineoplastic activity, whose antineoplastic mechanism of action is unknown.
4-Allylcatechol is an intermediate to synthetic safrole and was used in a study performed to evaluate the phenolic content, antioxidant and antimicrobial activi...
Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits pro...
Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezi...
FH1 (BRD-K4477) is a small molecule, which promotes the maturation and differentiation of induced pluripontent stem cells (iPSCs) to hepatocytes. FH 1 treatment...
This bio-active molecular is a broad-spectrum antibiotic that has potent Gram positive activity and Gram negative coverage. Brilacidin is highly effective in tr...
APCP-363 a bio-active chemical.