Dexmecamylamine - CAS 107538-05-6
Catalog number:
107538-05-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C11H21N
Molecular Weight:
167.29
COA:
Inquire
Targets:
Others
Description:
Dexmecamylamine is a nicotinic channel modulator with antidepressant activity. It demonstrated positive effects in a number of animal models of depression and anxiety. It was active in the forced swim test in rats. It was also active in the behavioral despair test in mice. It was used in the treatment of major depression and was in clinical phase 3 trials, but now it was terminated. It was developed by Targacept.
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Purity:
>98%
Appearance:
Solid powder
Synonyms:
TC-5214;TC5214;NIH-11008;NIH11008;(1S,3S,4R)-N,2,2,3-tetramethylbicyclo[2.2.1]heptan-3-amine
Solubility:
10 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Dexmecamylamine was used in the treatment of major depression.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Boiling Point:
189.3±8.0 °C | Condition: Press: 760 Torr
Density:
0.91±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
IMYZQPCYWPFTAG-NGZCFLSTSA-N
InChI:
InChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3/t8-,9+,11-/m0/s1
Canonical SMILES:
CC1(C2CCC(C2)C1(C)NC)C
Current Developer:
Dexmecamylamine was in clinical phase 3 trials, but now it was terminated. It was developed by Targacept.
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Chemical Structure

CAS 107538-05-6 Dexmecamylamine

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