|Description||Dexmecamylamine is a nicotinic channel modulator with antidepressant activity. It demonstrated positive effects in a number of animal models of depression and anxiety. It was active in the forced swim test in rats. It was also active in the behavioral despair test in mice. It was used in the treatment of major depression and was in clinical phase 3 trials, but now it was terminated. It was developed by Targacept.|
|Solubility||10 mM in DMSO|
|Application||Dexmecamylamine was used in the treatment of major depression.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||189.3±8.0 °C | Condition: Press: 760 Torr|
|Density||0.91±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
|Current Developer||Dexmecamylamine was in clinical phase 3 trials, but now it was terminated. It was developed by Targacept.|
A selective FAP inhibitor (Ki= 23 nM)
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