Dexamethasone Acetate - CAS 1177-87-3
Catalog number: B0084-300600
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C24H31FO6
Molecular Weight:
434.50
COA:
Inquire
Targets:
Glucocorticoid Receptor
Description:
The acetate-protect form of Dexamethasone which is a glucocorticoid and could be used as a anti-inflammatory agent.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-300600 5 g $399 In stock
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Brife Description:
glucocorticoid, anti-inflammatory agent
Purity:
95%
Appearance:
White or almost white crystalline powder
Synonyms:
Dexamethasone 21-acetate; Decadronal; Panasone; Dexamethasone acetate anhydrous; Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11.beta.,16.alpha.)-; AC1L1GH2
Solubility:
DMSO: 87 mg/mL, H2O : < 0.1 mg/mL
Storage:
2-8ºC
MSDS:
Inquire
Application:
The acetate-protect form of Dexamethasone which is a glucocorticoid and could be used as a anti-inflammatory agent.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Boiling Point:
579.4ºC at 760 mmHg
Melting Point:
238-240ºC
Density:
1.3 g/cm3
InChIKey:
AKUJBENLRBOFTD-RPRRAYFGSA-N
InChI:
InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
Canonical SMILES:
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)C)O)C)O)F)C
1.Topical delivery of dexamethasone acetate from hydrogel containing nanostructured liquid carriers and the drug.
Tung NT1, Huyen VT2, Chi SC3. Arch Pharm Res. 2015 Nov;38(11):1999-2007. doi: 10.1007/s12272-015-0608-5. Epub 2015 May 5.
The potential of hydrogel containing nanostructured lipid carriers (NLC) to enhance the skin permeation rate and skin deposition of dexamethasone acetate (DEA) was investigated. The particle size of obtained NLCs was around 224.4 nm. NLCs had core-shell structure and DEA existed in amorphous state in NLCs. The permeation rate of DEA through excised mouse skins from hydrogel containing DEA-NLC (DEA-NLC-hydrogel) was 7.3 times higher than DEA-ointment. The skin deposition of DEA from DEA-NLC-hydrogel increased 3.8 folds compared to that from solution of DEA in hydrogel (DEA-hydrogel).
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