|Description||Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.|
|Synonyms||SCH-34117, NSC 675447|
Triprolidine hydrochloride is a potent H1 histamine receptor antagonist. It is used in allergic rhinitis, urticaria and asthma. It is an over-the-counter antihi...
Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.
GS-283, an isoquinolin derivative, has been found to be histamine receptor and muscarinic receptor blocker.
Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...
Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic r...
Brompheniramine hydrogen maleate
Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
KP136, an antiallergic agent, remarkably inhibited the passive cutaneous anaphylaxis (PCA) with intravenous and oral dosing. KP-136 is an oral potent inhibitor ...
Epinastine is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is highly selective for ...
The hydrochloride salt form of Decloxizine, a hydroxyzine analogue, is a histamine 1 receptor antagonist and often known as an impurity of Hydroxyzine.
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.
Pheniramine Maleate is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.
Halopyramine is known as a competitive reversible H1-receptor antagonist. It exerts its pharmacological action by competing with histamine for the H1 subtype hi...
OUP16 is a potent and selective histamine H4 receptor(hH4R) agonist with 40-fold selectivity over the hH3R and superior to its (2S,5S)-configured optical antipo...
Tripelennamine hydrochloride, the hydrochloride salt form of tripelennamine, is a blood-brain barrier penetrant and orally active H1-receptor antagonist. Tripel...
Betahistine is a H1 receptor agonist, which serves as a vasodilator. It is used in Meniere disease and in vascular headaches but may exacerbate bronchial asthma...
Mianserin is a tetracyclic second generation antidepressant. It has the same efficacy as the tricyclics, but has no anticholinergic and cardiovascular side-effe...
Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.
Zaltidine is an effective but hepatotoxic H2-receptor antagonist. It has higher incidence of hepatic damage than with commonly used H2-receptor antagonists. It ...
JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other h...
Bavisant dihydrochloride hydrate
The dihydrochloride hydrate salt form of Bavisant which is an orally bioavaliable and selective H3 receptor antagonist that could probably useful in the treatme...