Dermorphin - CAS 77614-16-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C40H50N8O10
Molecular Weight:
802.87
COA:
Inquire
Targets:
Opioid Receptor
Description:
Dermorphin, a naturally occurring heptapeptide originally found in the skin of amphibians, is a μ-opioid receptor(MOR) agonist with analgesic and antinociceptive effects.
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Sequence:
YAFGYPS
Synonyms:
H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2; L-tyrosyl-D-alanyl-L-phenylalanyl-glycyl-L-tyrosyl-L-prolyl-L-serinamide; (2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide; YAFGYPS
Solubility:
DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
1323.8±65.0 ℃ at 760 Torr
Melting Point:
157-159 ℃
Density:
1.363±0.06 g/cm3
InChIKey:
FHZPGIUBXYVUOY-VWGYHWLBSA-N
InChI:
1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1
Canonical SMILES:
CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NCC(=O)NC(CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)NC(CO)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)O)N
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Chemical Structure

CAS 77614-16-5 Dermorphin

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