Demeclocycline HCl - CAS 64-73-3
Catalog number:
64-73-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H21ClN2O8·HCl
Molecular Weight:
501.31
COA:
Inquire
Targets:
Antibacterial
Description:
Demeclocycline HCl is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.
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Purity:
>98%
Synonyms:
NCI-c55561
MSDS:
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1.Study of osteogenesis in adult sheep on a high and a low calcium ration by means of fluorescing bone markers.
van de Braak AE, van 't Klooster AT. Vet Res Commun. 1987;11(2):101-8.
The rate of osteogenesis was studied in 8 non-pregnant, non-lactating Friesian dairy sheep, 3-6 years old, by means of a treatment with 3 different bone seeking agents. Four sheep were fed a low calcium ration (LCa:1.8 g Ca/d) and four other sheep a high calcium ration (HCa:12.7 g Ca/d). The bone markers, oxytetracycline-HCl, alizarine-complexion and demeclocycline-HCl, were administered at intervals of 6 weeks, and the sheep were killed 1 week after administration of the last marker. In undecalcified cross sections from the middle of ribs 2, 10 and 12, and from the proximal and distal parts of rib 10, the numbers of labelled osteons and the number of osteons with 1, 2 or 3 markers were counted under fluorescent microscopy. In the ribs of sheep from the LCa group, the number of labelled osteons and the quantity of labels per osteon tended to be higher than those of sheep from the HCa group. When osteogenic activity was compared in the different sites of ribs analysed, lowest osteogenic activity was observed in the proximal part of the 10th rib.
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CAS 64-73-3 Demeclocycline HCl

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