delta-DODECALACTONE - CAS 713-95-1
Molecular Formula:
C12H22O2
Molecular Weight:
198.31
COA:
Inquire
Olfactive Family:
Butter | Fruity
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FEMA:
2401
Odor description:
Fruity, peach-like and buttery aroma.
Taste description:
Characteristic fresh butter taste, used in conjuction with delta decalactone.
Purity:
99.0% (sum of isomers)
Appearance:
colorless liquid
Synonyms:
2H-Pyran-2-one, 6-heptyltetrahydro-, 5-Dodecanolide, 5-Hydroxydodecanoic acid, delta-lactone, 6-Heptyltetrahydro-2H-pyran-2-one, delta-DODECALACTONE FCC, delta-Heptyl-delta-valerolactone, delta-Heptylvalerolactone, Dodecan-5-olide
Solubility:
Insoluble in water; soluble in alcohol.
Storage:
Store tightly sealed under inert gas in a cool, well-ventilated area.
MSDS:
Inquire
Shelf Life:
18 months from manufacture date
Boiling Point:
312.73 C (EPI 4.0)
Specificgravity:
0.942 : 0.950 at 25 deg C
Refractive index:
1.458 : 1.461 at 20 deg C
1.Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver.
Kondo Y1, Ishigami A, Kubo S, Handa S, Gomi K, Hirokawa K, Kajiyama N, Chiba T, Shimokado K, Maruyama N. FEBS Lett. 2004 Jul 16;570(1-3):57-62.
Senescence marker protein-30 (SMP30) was originally identified as a novel protein in the rat liver, the expression of which decreases androgen-independently with aging. We have now characterized a unique property of SMP30, the hydrolysis of diisopropyl phosphorofluoridate (DFP), which is similar to the chemical warfare nerve agents sarine, soman and tabun. Hydrolysis of DFP was stimulated equally well by 1 mM MgCl2, MnCl2 or CoCl2, to a lesser extent by 1 mM CdCl2 but not at all by 1 mM CaCl2. No 45Ca2+-binding activity was detected for purified SMP30, suggesting that SMP30 is not a calcium-binding protein, as others previously stated. Despite the sequence similarity between SMP30 and a serum paraoxonase (PON), the inability of SMP30 to hydrolyze PON-specific substrates such as paraoxon, dihydrocoumarin, gamma-nonalactone, and delta-dodecanolactone indicate that SMP30 is distinct from the PON family. We previously established SMP30 knockout mice and have now tested DFPase activity in their livers.
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