|Description||Deferasirox Fe3+ chelate is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias.|
|Synonyms||Exjade Fe3+ chelate|
TDFA is a protein arginine deiminase 4 (PAD4) inhibitor (IC50 = 2.3, 8.5, 26 and 71 μM for PAD4, PAD1, PAD3 and PAD2, respectively) used for the treatment of au...
CP-472555 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in a...
PIT 1 is an apoptosis inducing selective PIP3 antagonist which has been shown to inhibit the binding of PIP3 to the pleckstrin homology (PH) domain of Akt (IC50...
Fatostatin A hydrobromide
Fatostatin A is an inhibitor of sterol regulatory element binding protein (SREBP). Fatostatin A reverses hyperglycemia in diabetic (ob/ob) mice, and inhibits pr...
17α-Hydroxyprogesterone Caproate , a synthetic steroidal progestin, is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid used in the treat...
ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer cell lines harboring at least one mutated BRAF allele. BRAF mu...
SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibit...
Lomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.
A-92 inhibits the stress response of general control nonderepressible 2 kinase (GCN2 or EIF2AK4) (IC50 value of <0.3 μM). It is potentially used as a chemothera...
Clioxanide is an anthelmintic agent.
LY 186564 is a bio-active chemical,but no detailed information has been published yet.
Isoxazole 9 (ISX-9)
Isoxazole 9 (Isx-9) is a synthetic promotor of adult neurogenesis by triggering neuronal differentiation of adult neural stem/precursor cells (NSPCs).
Astragaloside II is a saponin found in the root of Astragalus membranaceus (Fisch.) Bunge, which is known as huáng qí in Traditional Chinese Medicine. It has ca...
AZ PFKFB3 26
AZ PFKFB3 26 is a selective and potent metabolic kinase PFKFB3 inhibitor with IC50 value of 0.023 μM. It is selective for PFKFB3 over PFKFB1 and PFKFB2 isoforms...
Isorhamnetin-3-O-beta-D-Glucoside from S. herbacea is a leading compound for further study as a new drug for the prevention and/or treatment of diabetes and its...
Ono-1082 increases cAMP levels in hepatocytes in rats.
N-Cyclopropyl-N-methyl-2-Aminotetraline hydrobromide is a MAO inhibitor.
S Tag Peptide, a 15 amino acid peptide derived from RNase A, is an oligopeptide used for improving protein solubility.
Bz 423 has been found to be an ATP synthase inhibitor and could suppress disease in lupus-prone mice at some extent.
Bergenin is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid.It shows a potent immunomodulatory effect.