Decloxizine hydrochloride - CAS 13073-96-6
Catalog number: 13073-96-6
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C21H28N2O2?2ClH
Molecular Weight:
413.39
COA:
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Targets:
Histamine Receptor
Description:
The hydrochloride salt form of Decloxizine, a hydroxyzine analogue, is a histamine 1 receptor antagonist and often known as an impurity of Hydroxyzine.
Purity:
95%
Appearance:
Powder
Synonyms:
2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol Hydrochloride; 1-[2-(2-Hydroxyethoxy)ethyl]-4-α-phenylbenzyldiethylenediamine Dihydrochloride; Autokar; Hydroxydiethylphenamine; Rescupal; UCB 1402; UCB1402; UCB-1402
Solubility:
10 mM in DMSO
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
The hydrochloride salt form of Decloxizine is a histamine 1 receptor antagonist and often known as an impurity of Hydroxyzine.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Boiling Point:
472.4ºC at 760mmHg
Density:
1.115g/cm3
InChIKey:
RBSDUJACXBVDDN-UHFFFAOYSA-N
InChI:
InChI=1S/C21H28N2O2.2ClH/c24-16-18-25-17-15-22-11-13-23(14-12-22)21(19-7-3-1-4-8-19)20-9-5-2-6-10-20;;/h1-10,21,24H,11-18H2;2*1H
Canonical SMILES:
C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=CC=C3.Cl.Cl
1.[Simultaneous determination of three components in compound clorprenaline tablet by using the derivative-complementary tristimulus method].
Li QY1, Zhuo ZL, Chen YW. Yao Xue Xue Bao. 1990;25(5):357-61.
Clorprenaline hydrochloride (a), bromhexine hydrochloride (b) and decloxizine hydrochloride (c) are three main components in clorprenaline compound tablet. The serious overlapping bands of their absorption spectra cause the interference in the determinations, especially the component of (a) which has both minor content and low absorption coefficient, thus making the analysis difficult. In this paper, the interference from matrix is eliminated by using first order derivative transformation. In combination with complementary tristimulus method and with the technique of additions, the concentrations of three components in tablets can be successfully determined simultaneously. A software developed in this laboratory makes possible the ease of parameter selection, reporting data in various formats and printing figures of dissolution process, showing a clear locus. This method will be of value to quality control in manufacturing process and to the research of the dissolution dynamics of tablets in simulated stomach.
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CAS 13073-96-6 Decloxizine hydrochloride

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