|Molecular Formula||C10H16N5O12P3 (free acid)|
|Molecular Weight||491.18 (free acid)|
|Structure\Application||Other modified nucleotides | Nucleotides applied on DNA/RNA|
|Description||ddGTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddGTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dGTP in cells.|
|Brife Description||inhibitor of reverse transcriptases from retroviruses|
|Purity||≥ 98% by HPLC, functionally tested by chain termination sequencing reactions|
|Appearance||clear aqueous solution|
|Synonyms||2',3'-Dideoxyguanosine-5'-triphosphate, Lithium salt|
|Application||ddGTP is an inhibitor of reverse transcriptases from retroviruses.|
CMP-CP is a non-hydrolytic analogue of CDP. It is commonly used as a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates.
The lyophilized form of dCTP. dCTP is a nucleoside triphosphate used in DNA synthesis by being incorporated into DNA strand.
dPTP could be used in the studies of DNA polymerases (through interactions) and the generationg of a library of mutants.
pG(2',5')pA is a potential metabolite of 2'3'-cGAMP, the metazoan cyclic dinucleotide second messenger.
CDP-Gel is the CDP coupled to a polymeric gel by the terminal phosphate, which can be used in the affinity purification of sialyltransferases.
pApA is a potential metabolite of c-diAMP, an additional purine-based signalling nucleotide in prokaryotes.
5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug.
The solution form of ATP, a nucleotide and a small molecule used in cells as a coenzyme.
The lyophilized form of ATP, a nucleotide and a small molecule used in cells as a coenzyme.
ddCTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddCTP is commonly used to termina...
dTTP could be used in the studies of DNA labeling reactions, polymerase chain reaction and sequencing/cycle sequencing analysis.
6-cHe-ADP is a precursor in the synthesis of the corresponding radio-labelled triphosphate used in the chemical genetics approach.
The lithium salt solution form of dATP. dATP is a purine nucleoside triphosphate used in the synthesis of DNA by being incorporated into DNA.