|Molecular Formula||C10H16N5O12P3 (free acid)|
|Molecular Weight||491.18 (free acid)|
|Structure\Application||Other modified nucleotides | Nucleotides applied on DNA/RNA|
|Description||ddGTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddGTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dGTP in cells.|
|Brife Description||inhibitor of reverse transcriptases from retroviruses|
|Purity||≥ 98% by HPLC, functionally tested by chain termination sequencing reactions|
|Appearance||clear aqueous solution|
|Synonyms||2',3'-Dideoxyguanosine-5'-triphosphate, Lithium salt|
|Application||ddGTP is an inhibitor of reverse transcriptases from retroviruses.|
4-Thio-UTP is an agonist of P2Y2 and P2Y4 receptors that can influence on transcription process to terminate chain extension.
TMP-CP is a non-hydrolytic analogue of thymidine-5'-diphosphate and an inhibitor of thymidine kinase. It is also used as a starting structure in the synthesis o...
2'-CMP is a metabolite of cytidine-2',3'-cyclic monophosphate.
dUTP solution - Sodium Salt
dUTP has been found to be useful in the studies of distribution, specificity and kinetics of dUTPase.
GpAp is a synthetic linear dinucleotide not binding to the c-diGMP-I riboswitch.
6-cHe-ATP is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
dTTP - lyophilized
dTTP could be used in the studies of DNA labeling reactions, polymerase chain reaction and sequencing/cycle sequencing analysis.
2-Fluoro-ATP is a toxic metabolite of 9-β-D-arabinosyl-2-fluoroadenine, an anticancer drug. 2-Fluoro-ATP is commonly used as a versatile tool for 19F NMR-based ...
The lyophilized form of CTP. CTP is a P2X purinergic receptor agonist that can be used in the synthesis of RNA. In metabolic reactions, it acts as a coenzyme.
2'-GMP is a metabolite of guanosine-2',3'-cyclic monophosphate.
2-Hydroxy-dATP is an oxidized form of dATP with a mutagenic effect, which is generated by being incorporated opposite G by Escherichia coli DNA polymerase III.
6-PhEt-ATP is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach) and to research CFTR gating.
ddNTP bundle is a mixture of ddATP, ddTTP, ddGTP and ddCTP. ddNTP is an inhibitor of DNA polymerase used to terminate chain extension.