ddGTP - CAS 68726-28-3
Catalog number: 68726-28-3
Category: Nucleotides
Molecular Formula:
C10H16N5O12P3 (free acid)
Molecular Weight:
491.18 (free acid)
COA:
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Structure\Application:
Other modified nucleotides | Nucleotides applied on DNA/RNA
Description:
ddGTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddGTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dGTP in cells.
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Brife Description:
inhibitor of reverse transcriptases from retroviruses
Purity:
≥ 98% by HPLC, functionally tested by chain termination sequencing reactions
Appearance:
clear aqueous solution
Synonyms:
2',3'-Dideoxyguanosine-5'-triphosphate, Lithium salt
MSDS:
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Application:
ddGTP is an inhibitor of reverse transcriptases from retroviruses.
InChIKey:
HDRRAMINWIWTNU-NTSWFWBYSA-N
InChI:
InChI=1S/C10H16N5O12P3/c11-10-13-8-7(9(16)14-10)12-4-15(8)6-2-1-5(25-6)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h4-6H,1-3H2,(H,20,21)(H,22,23)(H2,17,18,19)(H3,11,13,14,16)/t5-,6+/m0/s1
Canonical SMILES:
C1CC(OC1COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N2C=NC3=C2NC(=NC3=O)N
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CAS 68726-28-3 ddGTP

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