ddATP - CAS 24027-80-3
Catalog number: 24027-80-3
Category: Nucleotides
Molecular Formula:
C10H16N5O11P3 (free acid)
Molecular Weight:
475.18 (free acid)
COA:
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Structure\Application:
Other modified nucleotides | Nucleotides applied on DNA/RNA
Description:
ddATP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddATP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dATP in cells.
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Brife Description:
inhibitor of reverse transcriptases from retroviruses
Purity:
≥ 98% by HPLC, functionally tested by chain termination sequencing reactions
Appearance:
clear aqueous solution
Synonyms:
2',3'-Dideoxyadenosine-5'-triphosphate, Lithium salt
MSDS:
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Application:
ddATP is an inhibitor of reverse transcriptases from retroviruses.
InChIKey:
OAKPWEUQDVLTCN-NKWVEPMBSA-N
InChI:
InChI=1S/C10H16N5O11P3/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(24-7)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h4-7H,1-3H2,(H,19,20)(H,21,22)(H2,11,12,13)(H2,16,17,18)/t6-,7+/m0/s1
Canonical SMILES:
C1CC(OC1COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N2C=NC3=C2N=CN=C3N
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