|Molecular Formula||C9H16N3O12P3S (free acid)|
|Molecular Weight||483.22 (free acid)|
|Structure\Application||Phosphate modified Nucleotides|
|Purity||≥ 95% by HPLC|
|Appearance||clear aqueous solution|
|Synonyms||2'-Deoxycytidine-5'-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers)|
ddGTP-α-S is used in mass spectrometric genotyping.
ddTTP-α-S is used in mass spectrometric genotyping.
6-Fu-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
ATPγS is an agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, used as a reagent in...
ddATP-α-S is used in mass spectrometric genotyping.
Rp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable.
Mant-GTPγS had lower affinities for Gαs and Gαi than GTPγS/GppNHp as assessed by inhibition of GTP hydrolysis of receptor-Gα fusion proteins. MANT-GTPγS was muc...