|Description||DCPG is a potent and selective mGlu8a agonist (EC50 = 31 nM) displaying > 100-fold selectivity over mGlu1-7. It increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo.|
|Brife Description||mGlu8a agonist|
|Purity||≥98% by HPLC|
|Synonyms||(S)-3,4-DCPG; (S)-3,4-Dicarboxyphenylglycine; 4-[Amino(carboxy)methyl]phthalic acid|
CBiPES hydrochloride is a selective positive allosteric modulator of the mGlu2 receptor (IC50 = 98.2 nM).
(RS)-PPG is a potent and selective group III metabotropic glutamate receptor (mGluR) agonist, with approximately 25-fold selectivity for hmGlu8. (RS)-PPG exhibi...
Z-Cyclopentyl-AP4 is a group III mGlu receptor agonist with higher potency at mGlu4 than mGlu8 (EC50 = 49 and 124 μM, respectively). Z-Cyclopentyl-AP4 selective...
Lu AF21934 is a selective and brain-penetrating positive allosteric modulator (PAM) of mGlu4 receptors (IC50= 500 nM) on the harmaline-induced tremor and other ...
LY 456236 hydrochloride
LY 456236 hydrochloride is a mGlu1 receptor antagonist with IC50 value of 143 nM. It may be used in the treatment of chronic pain.
LY-404,039, also known as pomaglumetad, is an amino acid analog drug that acts as a highly selective agonist for the metabotropic glutamate receptor group II su...
MSPG is a non-selective antagonist of presynaptic mGluRs.
L-AP4 is a selective group III metabotropic glutamate receptor (mGluR) agonist. It also acts as an agonist at the quisqualate-sensitized AP6 site in hippocampus...