DC-05 - CAS 890643-16-0
Catalog number:
890643-16-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H25N3O
Molecular Weight:
383.49
COA:
Inquire
Targets:
DNMT
Description:
DC-05 is a potent and selective non-nucleoside DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 10.3 uM. It has significant selectivity toward other AdoMet-dependent protein methyltransferases. It significantly inhibits cancer cell proliferation. It inhibitis DNMT1 by binding to DNMT1 instead of incorporating into DNA.
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Purity:
>98 %
Appearance:
White to off-white Solid
Synonyms:
1-Carbazol-9-yl-3-[2-(1H-indol-3-yl)ethylamino]propan-2-ol
Solubility:
10 mM in DMSO
Storage:
2-8ºC
MSDS:
Inquire
Application:
DC-05 inhibits cancer cell proliferation.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Boiling Point:
667.5±55.0 °C | Condition: Press: 760 Torr
Density:
1.23±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
LJWMTSMUQJNHOC-UHFFFAOYSA-N
InChI:
InChI=1S/C25H25N3O/c29-19(16-26-14-13-18-15-27-23-10-4-1-7-20(18)23)17-28-24-11-5-2-8-21(24)22-9-3-6-12-25(22)28/h1-12,15,19,26-27,29H,13-14,16-17H2
Canonical SMILES:
C1=CC=C2C(=C1)C(=CN2)CCNCC(CN3C4=CC=CC=C4C5=CC=CC=C53)O
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