Dapoxetine hydrochloride - CAS 129938-20-1
Catalog number:
129938-20-1
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H23NO.HCl
Molecular Weight:
341.87
COA:
Inquire
Targets:
SSRIs
Description:
Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor.
Publictions citing BOC Sciences Products
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Purity:
>98%
Synonyms:
LY-210448
MSDS:
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1.Thermal Analysis Investigation of Dapoxetine and Vardenafil Hydrochlorides using Molecular Orbital Calculations.
Attia AK1, Souaya ER2, Soliman EA1. Adv Pharm Bull. 2015 Nov;5(4):523-9. doi: 10.15171/apb.2015.071. Epub 2015 Nov 30.
PURPOSE: Thermal analysis techniques have been used to study the thermal behavior of dapoxetine and vardenafil hydrochlorides and confirmed using semi-empirical molecular orbital calculations.
2.Comparison of Treatment Emergent Adverse Events in Men With Premature Ejaculation Treated With Dapoxetine and Alternate Oral Treatments: Results From a Large Multinational Observational Trial.
Verze P1, Cai T2, Magno C3, Sabella F4, Cucchiara V4, Palmieri A4, Mirone V4. J Sex Med. 2016 Feb;13(2):194-9. doi: 10.1016/j.jsxm.2015.12.017. Epub 2016 Jan 21.
INTRODUCTION: Dapoxetine (DPX) has a pharmacokinetic profile suggesting a low rate of class-related adverse events (AEs).
3.Multivariate Approaches for Simultaneous Determination of Avanafil and Dapoxetine by UV Chemometrics and HPLC-QbD in Binary Mixtures and Pharmaceutical Product.
J AOAC Int. 2016 Apr 7. [Epub ahead of print]
Multivariate UV-spectrophotometric methods and Quality by Design (QbD) HPLC are described for concurrent estimation of avanafil (AV) and dapoxetine (DP) in the binary mixture and in the dosage form. Chemometric methods have been developed, including classical least-squares, principal component regression, partial least-squares, and multiway partial least-squares. Analytical figures of merit, such as sensitivity, selectivity, analytical sensitivity, LOD, and LOQ were determined. QbD consists of three steps, starting with the screening approach to determine the critical process parameter and response variables. This is followed by understanding of factors and levels, and lastly the application of a Box-Behnken design containing four critical factors that affect the method. From an Ishikawa diagram and a risk assessment tool, four main factors were selected for optimization. Design optimization, statistical calculation, and final-condition optimization of all the reactions were Carried out.
4.The Asia-Pacific Flexible Dose Study of Dapoxetine and Patient Satisfaction in Premature Ejaculation Therapy: The PASSION Study.
McMahon C1, Lee SW2, Kim SW3, Moon du G4, Kongkanand A5, Tantiwongse K5. Sex Med. 2016 Mar;4(1):e18-27. doi: 10.1016/j.esxm.2015.12.006.
INTRODUCTION: Dapoxetine is a short-acting selective serotonin reuptake inhibitor for treatment of premature ejaculation (PE).
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 129938-20-1 Dapoxetine hydrochloride

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