Dabcyl-YVADAPV-EDANS - CAS 161877-70-9
Molecular Formula:
C61H76N12O14S
Molecular Weight:
1233.4
COA:
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Application\Fluorophore:
Fluorescent Enzyme Substrates
Description:
Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1. EDANS is released upon enzymatic cleavage by caspase-1 at the Ala-Ser site, of which the fluorescence can be used to quantify caspase-1 activity.
Sequence:
Dabcyl-Tyr-Val-Ala-Asp-Ala-Pro-Val-edans
Purity:
≥95%
Synonyms:
Dabcyl-ICE-EDANS; N-[4-[[4-(dimethylamino)phenyl]azo]benzoyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-valinamide
Storage:
Store at -20°C
MSDS:
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InChIKey:
VOOSFUAACNZZDI-NCIMJASNSA-N
InChI:
InChI=1S/C61H76N12O14S/c1-34(2)52(59(82)63-30-29-62-46-14-9-13-45-44(46)12-10-16-50(45)88(85,86)87)69-58(81)49-15-11-31-73(49)61(84)37(6)65-56(79)48(33-51(75)76)66-54(77)36(5)64-60(83)53(35(3)4)68-57(80)47(32-38-17-27-43(74)28-18-38)67-55(78)39-19-21-40(22-20-39)70-71-41-23-25-42(26-24-41)72(7)8/h9-10,12-14,16-28,34-37,47-49,52-53,62,74H,11,15,29-33H2,1-8H3,(H,63,82)(H,64,83)(H,65,79)(H,66,77)(H,67,78)(H,68,80)(H,69,81)(H,75,76)(H,85,86,87)/b71-70+/t36-,37-,47-,48-,49-,52-,53-/m0/s1
Canonical SMILES:
CC(C)C(C(=O)NCCNC1=CC=CC2=C1C=CC=C2S(=O)(=O)O)NC(=O)C3CCCN3C(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C5=CC=C(C=C5)N=NC6=CC=C(C=C6)N(C)C
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Chemical Structure

CAS 161877-70-9 Dabcyl-YVADAPV-EDANS

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